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Emi Nosaka

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Articles 6
Citations 83
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Recent Articles
1.
Honma D, Kanno O, Watanabe J, Kinoshita J, Hirasawa M, Nosaka E, et al.
Cancer Sci . 2017 Jul; 108(10):2069-2078. PMID: 28741798
Polycomb repressive complex 2 (PRC2) methylates histone H3 lysine 27 and represses gene expression to regulate cell proliferation and differentiation. Enhancer of zeste homolog 2 (EZH2) or its close homolog...
2.
Nakagami Y, Kawase Y, Yonekubo K, Nosaka E, Etori M, Takahashi S, et al.
Biol Pharm Bull . 2010 Jun; 33(6):1067-9. PMID: 20522980
CC chemokine receptor 4 (CCR4) is generally recognized as a preferential marker for T helper 2 cells, and we have previously reported morpholine-derivative CCR4 antagonists, RS-1154 and RS-1269. Here, we...
3.
Tsuchida H, Takahashi S, Nosaka E, Kuraya T, Yamashita M, Morimoto K
Eur J Pharmacol . 2008 Aug; 596(1-3):153-9. PMID: 18706408
Neurokinins are known to induce neurogenic inflammation related to respiratory diseases. The effects of CS-003 ([1-{2-[(2R)-(3,4-dichlorophenyl)-4-(3,4,5-trimethoxybenzoyl)morpholin-2-yl]ethyl}spiro[benzo[c]thiophene-1(3H),4'-piperidine]-(2S)-oxide hydrochloride]), a novel triple neurokinin receptor antagonist, on several respiratory disease models were evaluated...
4.
Tsuchida H, Takahashi S, Nosaka E, Mukaiyama O, Yamashita M, Morimoto K
Eur J Pharmacol . 2008 Mar; 586(1-3):306-12. PMID: 18353309
Neurokinins are known to induce neurogenic inflammation related to respiratory diseases, though there is little information on triple neurokinin receptor antagonists. The pharmacological properties of the novel triple neurokinin 1,...
5.
Mukaiyama O, Morimoto K, Nosaka E, Takahashi S, Yamashita M
Eur J Pharmacol . 2004 Sep; 498(1-3):287-94. PMID: 15364007
In this study, we investigated the involvement of neurokinin NK3 receptors in a severe asthma model prepared by administering ovalbumin via inhalation three times to systemically sensitized guinea pigs. [3H]senktide,...
6.
Mukaiyama O, Morimoto K, Nosaka E, Takahashi S, Yamashita M
Int Arch Allergy Immunol . 2004 Jun; 134(4):263-72. PMID: 15205557
Background: Involvement of neurokinins in asthma has been previously pointed out by several reports. However, the relationship between neurokinins and the severity of asthma has remained unclear. We developed a...