Emeline L Maillet
Overview
Explore the profile of Emeline L Maillet including associated specialties, affiliations and a list of published articles.
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16
Citations
628
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Recent Articles
1.
Family N, Hendricks P, Williams L, Luke D, Krediet E, Maillet E, et al.
J Psychopharmacol
. 2022 Mar;
36(3):321-336.
PMID: 35253516
Background: Classic psychedelics hold promise as therapeutics for psychiatric disorders, but require scalable intervention protocols. This proof-of-concept study evaluated the safety, tolerability, pharmacokinetics, and subjective effects of 50, 75, and...
2.
Family N, Maillet E, Williams L, Krediet E, Carhart-Harris R, Williams T, et al.
Psychopharmacology (Berl)
. 2019 Dec;
237(3):841-853.
PMID: 31853557
Objective: This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of orally repeated administration of 5 μg, 10 μg, and 20 μg LSD in older healthy individuals. In the current...
3.
Flanagan T, Sebastian M, Battaglia D, Foster T, Maillet E, Nichols C
Sci Rep
. 2019 Sep;
9(1):13444.
PMID: 31530895
Coronary artery disease (CAD) is a progressive cardiovascular syndrome characterized by cholesterol-induced focal arterial lesions that impair oxygen delivery to the heart. As both innate and adaptive immune cells play...
4.
Kalueff A, Kaluyeva A, Maillet E
Behav Brain Res
. 2017 May;
330:63-67.
PMID: 28479267
Noribogaine is the main psychoactive metabolite of the hallucinogenic drug ibogaine, and is a particularly interesting compound potentially useful to treat dependence and various psychiatric disorders. Here, we report the...
5.
Walton K, Maillet E, Garcia J, Cardozo T, Galatzer-Levy I, Llinas R
Front Hum Neurosci
. 2017 Feb;
11:24.
PMID: 28217089
1-octanol is a therapeutic candidate for disorders involving the abnormal activation of the T-type calcium current since it blocks this current specifically. Such disorders include essential tremor and a group...
6.
Mash D, Ameer B, Prou D, Howes J, Maillet E
J Psychopharmacol
. 2016 Apr;
30(7):688-97.
PMID: 27044509
This study investigated the effects of noribogaine, the principal metabolite of the drug ibogaine, on substance-related disorders. In the first experiment, mice chronically treated with morphine were subjected to naloxone-precipitated...
7.
Maillet E, Cui M, Jiang P, Mezei M, Hecht E, Quijada J, et al.
Chem Senses
. 2015 Sep;
40(8):577-86.
PMID: 26377607
The sweet taste receptor, a heterodimeric G protein-coupled receptor comprised of T1R2 and T1R3, binds sugars, small molecule sweeteners, and sweet proteins to multiple binding sites. The dipeptide sweetener, aspartame...
8.
Maillet E, Milon N, Heghinian M, Fishback J, Schurer S, Garamszegi N, et al.
Neuropharmacology
. 2015 Aug;
99:675-88.
PMID: 26302653
Noribogaine is the long-lived human metabolite of the anti-addictive substance ibogaine. Noribogaine efficaciously reaches the brain with concentrations up to 20 μM after acute therapeutic dose of 40 mg/kg ibogaine...
9.
Chang Q, Hanania T, Mash D, Maillet E
J Psychopharmacol
. 2015 May;
29(6):704-11.
PMID: 25995321
Noribogaine, a polypharmacological drug with activities at opioid receptors, ionotropic nicotinic receptors, and serotonin reuptake transporters, has been investigated for treatment of substance abuse-related disorders. Smoking cessation has major benefits...
10.
Gomes I, IJzerman A, Ye K, Maillet E, Devi L
Mol Pharmacol
. 2011 Mar;
79(6):1044-52.
PMID: 21415307
It is becoming increasingly recognized that G protein-coupled receptors physically interact. These interactions may provide a mechanism for allosteric modulation of receptor function. In this study, we examined this possibility...