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Emanuele Murgo

Explore the profile of Emanuele Murgo including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 27
Followers 0
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Recent Articles
1.
Murgo E, Falco G, Serviddio G, Mazzoccoli G, Colangelo T
Cell Commun Signal . 2024 Jun; 22(1):319. PMID: 38858728
Several different signaling pathways that regulate cell proliferation and differentiation are initiated by binding of ligands to cell-surface and membrane-bound enzyme-linked receptors, such as receptor tyrosine kinases and serine-threonine kinases....
2.
Murgo E, Colangelo T, Bellet M, Malatesta F, Mazzoccoli G
Biology (Basel) . 2023 Oct; 12(10). PMID: 37887064
Neuronal PAS domain protein 2 (NPAS2) is a hemeprotein comprising a basic helix-loop-helix domain (bHLH) and two heme-binding sites, the PAS-A and PAS-B domains. This protein acts as a pyridine...
3.
Murgo E, De Santis E, Sansico F, Melocchi V, Colangelo T, Padovano C, et al.
J Exp Clin Cancer Res . 2023 Aug; 42(1):218. PMID: 37620852
Background: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy, characterized by restricted cellular subsets with asymmetrically enriched leukemia initiating cell (LIC) activity. Nonetheless, it is still unclear which...
4.
Melocchi V, Cuttano R, Murgo E, Mazzoccoli G, Bianchi F
Cancer Gene Ther . 2023 Jul; 30(10):1323-1329. PMID: 37479798
Increasing evidence imputes cancer progression and resistance to therapy to intra-tumor molecular heterogeneity set off by cancer cell plasticity. Re-activation of developmental programs strictly linked to epithelial-to-mesenchymal transition and gaining...
5.
Savino M, Guida C, Nardella M, Murgo E, Augello B, Merla G, et al.
Biomedicines . 2022 Dec; 10(12). PMID: 36551954
Heme is a member of the porphyrins family of cyclic tetrapyrroles and influences various cell processes and signalling pathways. Enzyme deficiencies in the heme biosynthetic pathway provoke rare human inherited...
6.
Colombini B, Dinu M, Murgo E, Lotti S, Tarquini R, Sofi F, et al.
Antioxidants (Basel) . 2022 Nov; 11(11). PMID: 36421414
Ageing is a multifactorial physiological manifestation that occurs inexorably and gradually in all forms of life. This process is linked to the decay of homeostasis due to the progressive decrease...
7.
Panelli P, De Santis E, Colucci M, Tamiro F, Sansico F, Miroballo M, et al.
Blood . 2022 Oct; 141(13):1597-1609. PMID: 36315912
T-cell acute lymphoblastic leukemia (T-ALL) is a T-cell malignancy characterized by cell subsets and enriched with leukemia-initiating cells (LICs). β-Catenin modulates LIC activity in T-ALL. However, its role in maintaining...
8.
Cei F, Chiarugi L, Brancati S, Montini M, Dolenti S, Stefano D, et al.
Biomed Pharmacother . 2022 Sep; 153:113454. PMID: 36076568
Background: Analysis of autopsy tissues obtained from patients who died from COVID-19 showed kidney tropism for SARS-COV-2, with COVID-19-related renal dysfunction representing an overlooked problem even in patients lacking previous...