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Emanuele Cacci

Explore the profile of Emanuele Cacci including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 971
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Recent Articles
1.
Diamanti T, Trobiani L, Mautone L, Serafini F, Gioia R, Ferrucci L, et al.
Traffic . 2024 Jan; 25(1):e12930. PMID: 38272450
Neuroligins are synaptic cell adhesion proteins with a role in synaptic function, implicated in neurodevelopmental disorders. The autism spectrum disorder-associated substitution Arg451Cys (R451C) in NLGN3 promotes a partial misfolding of...
2.
Giuliani A, Licursi V, Nisi P, Fiore M, DAngelo S, Biagioni S, et al.
Stem Cell Rev Rep . 2023 Aug; 19(8):2837-2851. PMID: 37605090
In the adult mouse brain, the subventricular zone (SVZ) underlying the lateral ventricles harbours a population of quiescent neural stem cells, which can be activated (aNSCs) to initiate proliferation and...
3.
Gioia R, Seri T, Diamanti T, Fimmano S, Vitale M, Ahlenius H, et al.
J Neurochem . 2022 Dec; 165(3):318-333. PMID: 36583243
Neuron generation persists throughout life in the hippocampus but is altered in animal models of neurological and neuropsychiatric diseases, suggesting that disease-associated decline in cognitive and emotional hippocampal-dependent behaviours might...
4.
Wang W, Di Nisio E, Licursi V, Cacci E, Lupo G, Kokaia Z, et al.
Life (Basel) . 2022 Nov; 12(11). PMID: 36362982
We analyzed the morphology and the transcriptomic changes of human neural stem progenitor cells (hNSPCs) grown on laminin in adherent culture conditions and subjected to simulated microgravity for different times...
5.
Quaresima S, Istiaq A, Jono H, Cacci E, Ohta K, Lupo G
Front Cell Dev Biol . 2022 Apr; 10:845567. PMID: 35450289
Neurogenesis persists in selected regions of the adult mouse brain; among them, the ventricular-subventricular zone (V-SVZ) of the lateral ventricles represents a major experimental paradigm due to its conspicuous neurogenic...
6.
Stronati E, Biagioni S, Fiore M, Giorgi M, Poiana G, Toselli C, et al.
Int J Mol Sci . 2021 Jul; 22(14). PMID: 34299185
Nervous system development involves proliferation and cell specification of progenitor cells into neurons and glial cells. Unveiling how this complex process is orchestrated under physiological conditions and deciphering the molecular...
7.
Morandell J, Schwarz L, Basilico B, Tasciyan S, Dimchev G, Nicolas A, et al.
Nat Commun . 2021 May; 12(1):3058. PMID: 34031387
De novo loss of function mutations in the ubiquitin ligase-encoding gene Cullin3 (CUL3) lead to autism spectrum disorder (ASD). In mouse, constitutive Cul3 haploinsufficiency leads to motor coordination deficits as...
8.
Licursi V, Anzellotti S, Favaro J, Sineri S, Carucci N, Cundari E, et al.
Sci Rep . 2020 Apr; 10(1):6562. PMID: 32300147
Exposure of the developing or adult brain to ionizing radiation (IR) can cause cognitive impairment and/or brain cancer, by targeting neural stem/progenitor cells (NSPCs). IR effects on NSPCs include transient...
9.
Poiana G, Gioia R, Sineri S, Cardarelli S, Lupo G, Cacci E
Neural Regen Res . 2020 Apr; 15(10):1773-1783. PMID: 32246617
In rodents, well characterized neurogenic niches of the adult brain, such as the subventricular zone of the lateral ventricles and the subgranular zone of the hippocampus, support the maintenance of...
10.
Stronati E, Conti R, Cacci E, Cardarelli S, Biagioni S, Poiana G
Int J Mol Sci . 2019 Jul; 20(15). PMID: 31357666
Neural stem progenitor cells (NSPCs) from E13.5 mouse embryos can be maintained in culture under proliferating conditions. Upon growth-factor removal, they may differentiate toward either neuronal or glial phenotypes or...