Else Kay Hoffmann
Overview
Explore the profile of Else Kay Hoffmann including associated specialties, affiliations and a list of published articles.
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17
Citations
235
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Recent Articles
1.
Sorensen B, Nielsen D, Thorsteinsdottir U, Hoffmann E, Lambert I
Am J Physiol Cell Physiol
. 2016 Mar;
310(11):C857-73.
PMID: 26984736
The leucine-rich repeat containing 8A (LRRC8A) protein is an essential component of the volume-sensitive organic anion channel (VSOAC), and using pharmacological anion channel inhibitors (NS3728, DIDS) and LRRC8A siRNA we...
2.
Kong S, Nohr-Nielsen A, Zeeberg K, Reshkin S, Hoffmann E, Novak I, et al.
Pancreas
. 2016 Jan;
45(7):1036-47.
PMID: 26765963
Objectives: Novel treatments for pancreatic ductal adenocarcinoma (PDAC) are severely needed. The aim of this work was to explore the roles of H-lactate monocarboxylate transporters 1 and 4 (MCT1 and...
3.
Lambert I, Enghoff M, Brandi M, Hoffmann E
Physiol Rep
. 2015 Jun;
3(6).
PMID: 26056062
The aim of this project was to analyze the regulation of p53 expression in NIH3T3 fibroblasts under the influence of increasing hyperosmotic stress. Expression of p53 showed a biphasic response...
4.
Sorensen B, Hartmann Rasmussen L, Broberg B, Klausen T, Sauter D, Lambert I, et al.
Cell Physiol Biochem
. 2015 May;
36(1):111-32.
PMID: 25925201
Background/aims: Altered expression of the integrin family of cell adhesion receptors has been associated with initiation, progression, and metastasis of solid tumors as well as in the development of chemoresistance....
5.
Hartmann Rasmussen L, Muller H, Jorgensen B, Pedersen S, Hoffmann E
Am J Physiol Cell Physiol
. 2014 Nov;
308(2):C101-10.
PMID: 25377086
The mechanisms linking cell volume sensing to volume regulation in mammalian cells remain incompletely understood. Here, we test the hypothesis that activation of nonreceptor tyrosine kinases Src, focal adhesion kinase...
6.
Hoffmann E, Holm N, Lambert I
IUBMB Life
. 2014 Apr;
66(4):257-67.
PMID: 24771413
The review describes molecular and functional properties of the volume regulated anion channel and Ca(2+)-dependent Cl(-) channels belonging to the anoctamin family with emphasis on physiological importance of these channels...
7.
Klausen T, Janssens A, Prenen J, Owsianik G, Hoffmann E, Pedersen S, et al.
Cell Calcium
. 2013 Dec;
55(1):38-47.
PMID: 24342753
The importance of the TRPV4 channel for human physiology has been highlighted in recent years with the identification of an increasing number of hereditary diseases associated with mutations of this...
8.
Kirkegaard S, Wulff T, Gammeltoft S, Hoffmann E
Cell Physiol Biochem
. 2013 Nov;
32(5):1238-46.
PMID: 24247225
Background/aims: Regulatory volume decrease (RVD) in response to acute cell swelling is well described and KCNK5 (also known as TASK-2 or K2P5.1) has been shown to be the volume sensitive...
9.
Hansen D, Friis M, Hoffmann E, Lambert I
J Membr Biol
. 2012 Mar;
245(2):77-87.
PMID: 22383044
The present work was initiated to investigate regulation of the taurine transporter TauT by reactive oxygen species (ROS) and the tonicity-responsive enhancer binding protein (TonEBP) in NIH3T3 mouse fibroblasts during...
10.
Hoffmann E
Cell Physiol Biochem
. 2011 Dec;
28(6):1061-78.
PMID: 22178996
This mini review outlines studies of cell volume regulation in two closely related mammalian cell lines: nonadherent Ehrlich ascites tumour cells (EATC) and adherent Ehrlich Lettre ascites (ELA) cells. Focus...