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Els Goetghebeur

Explore the profile of Els Goetghebeur including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 1191
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Recent Articles
1.
Thomassen D, Roychoudhury S, Amdal C, Reynders D, Musoro J, Sauerbrei W, et al.
BMC Med Res Methodol . 2025 Mar; 25(1):56. PMID: 40025441
Introduction: As patient-reported outcomes (PROs) are increasingly used in the evaluation of medical treatments, it is important that PROs are carefully analyzed and interpreted. This may be challenging due to...
2.
Prytula A, Reynders D, Goetghebeur E, Krupka K, Bacchetta J, Kanzelmeyer N, et al.
Pediatr Nephrol . 2025 Jan; PMID: 39865159
Background: We investigated factors associated with post-transplant growth in pediatric kidney transplant (KTx) recipients with a focus on plasma bicarbonate (HCO3) and estimated the effect of alkali treatment on growth....
3.
Thomassen D, Roychoudhury S, Amdal C, Reynders D, Musoro J, Sauerbrei W, et al.
BMC Med Res Methodol . 2024 Nov; 24(1):290. PMID: 39580440
Background: Patient-reported outcomes (PROs) play an increasing role in the evaluation of oncology treatments. At the same time, single-arm trials are commonly included in regulatory approval submissions. Because of the...
4.
Gabriel E, Sachs M, Waernbaum I, Goetghebeur E, Blanche P, Vansteelandt S, et al.
Biometrics . 2024 Jul; 80(3). PMID: 39036984
Recently, it has become common for applied works to combine commonly used survival analysis modeling methods, such as the multivariable Cox model and propensity score weighting, with the intention of...
5.
Keter A, Vanobberghen F, Lynen L, van Heerden A, Fehr J, Olivier S, et al.
PLoS One . 2024 Jun; 19(6):e0305126. PMID: 38857227
Background: Estimation of prevalence and diagnostic test accuracy in tuberculosis (TB) prevalence surveys suffer from reference standard and verification biases. The former is attributed to the imperfect reference test used...
6.
Gabriel E, Sachs M, Martinussen T, Waernbaum I, Goetghebeur E, Vansteelandt S, et al.
Stat Med . 2023 Dec; 43(3):534-547. PMID: 38096856
There are now many options for doubly robust estimation; however, there is a concerning trend in the applied literature to believe that the combination of a propensity score and an...
7.
Ost P, Siva S, Brabrand S, Dirix P, Liefhooghe N, Otte F, et al.
Eur Urol Oncol . 2023 Oct; 7(3):462-468. PMID: 37821242
Background: Treatment recommendations for patients with limited nodal recurrences are lacking, and different locoregional treatment approaches are currently being used. Objective: The aim of this trial is to compare metastasis-directed...
8.
Spaas M, Sundahl N, Kruse V, Rottey S, De Maeseneer D, Duprez F, et al.
JAMA Oncol . 2023 Jul; 9(9):1205-1213. PMID: 37410476
Importance: Although immune checkpoint inhibitors (ICIs) targeting programmed cell death 1 (PD-1) and PD-1 ligand 1 have improved the outcome for many cancer types, the majority of patients fails to...
9.
Liu L, Choi J, Musoro J, Sauerbrei W, Amdal C, Alanya A, et al.
Lancet Oncol . 2023 May; 24(5):e197-e206. PMID: 37142381
Patient-reported outcomes (PROs) are increasingly used in single-arm cancer studies. We reviewed 60 papers published between 2018 and 2021 of single-arm studies of cancer treatment with PRO data for current...
10.
Ciocanea-Teodorescu I, Goetghebeur E, Waernbaum I, Schon S, Gabriel E
Stat Med . 2023 Mar; 42(12):1946-1964. PMID: 36890728
Long-term register data offer unique opportunities to explore causal effects of treatments on time-to-event outcomes, in well-characterized populations with minimum loss of follow-up. However, the structure of the data may...