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Eloise Ferreira

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Articles 20
Citations 168
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Recent Articles
1.
Otgaar T, Bernert M, Morris G, Baichan P, Bignoux M, Letsolo B, et al.
Cell Mol Life Sci . 2025 Feb; 82(1):83. PMID: 39985566
Ageing is a degenerative process characterised by a decline in physiological functioning of the organism. One of the core regulators of cellular ageing are telomeres, repetitive DNA sequences of TTAGGG...
2.
Bernert M, Bignoux M, Madhav C, Gqeba S, Otgaar T, Morris G, et al.
FEBS Open Bio . 2024 May; 14(7):1072-1086. PMID: 38702074
Telomerase activity is directly affected by the laminin receptor precursor (LRP) protein, a highly conserved nonintegrin transmembrane receptor, which has been shown to have therapeutic effects in ageing, and age-related...
3.
Bignoux M, Otgaar T, Bernert M, Weiss S, Ferreira E
FEBS Open Bio . 2022 Dec; 13(2):323-340. PMID: 36579897
The incidence and mortality rates of cancer are growing rapidly worldwide, with lung cancer being the most commonly occurring cancer in males. Human carcinomas circumvent the inhibitory pathways induced by...
4.
Vania L, Morris G, Ferreira E, Weiss S
BMC Cancer . 2021 Apr; 21(1):392. PMID: 33836696
Background: The 37 kDa/67 kDa laminin receptor (LRP/LR) is involved in several tumourigenic-promoting processes including cellular viability maintenance and apoptotic evasion. Thus, the aim of this study was to assess...
5.
Cuttler K, Bignoux M, Otgaar T, Chigumba S, Ferreira E, Weiss S
J Alzheimers Dis . 2020 Jun; 76(2):753-768. PMID: 32568204
Background: Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) plaque and neurofibrillary tangle formation, respectively. Neurofibrillary tangles form as a result of the intracellular accumulation of hyperphosphorylated tau. Telomerase activity...
6.
Vania L, Morris G, Otgaar T, Bignoux M, Bernert M, Burns J, et al.
Expert Opin Ther Pat . 2019 Nov; 29(12):987-1009. PMID: 31722579
: The ubiquitously expressed 37 kDa/67 kDa high-affinity laminin receptor (laminin receptor precursor/laminin receptor, LRP/LR) is a protein found to play several roles within cells. The receptor is located in...
7.
Bignoux M, Cuttler K, Otgaar T, Ferreira E, Letsolo B, Weiss S
J Alzheimers Dis . 2019 May; 69(3):729-741. PMID: 31081791
Alzheimer's disease (AD) represents the most common form of neurodegenerative disorders with only palliative treatments currently available. Amyloid plaque formation caused by amyloid-β (Aβ) aggregation and neurofibrillary tangle formation caused...
8.
Ferreira E, Bignoux M, Otgaar T, Tagliatti N, Jovanovic K, Letsolo B, et al.
Oncotarget . 2018 Jun; 9(43):27059-27073. PMID: 29930750
Alzheimer's disease (AD) is a neurodegenerative disease caused by accumulation of amyloid beta (Aβ) plaque and neurofibrillary tangle formation. We have shown , that knock-down and blockade of the 37...
9.
Vania L, Rebelo T, Ferreira E, Weiss S
BMC Cancer . 2018 May; 18(1):602. PMID: 29843646
Background: Cancer remains one of the leading causes of death around the world, where incidence and mortality rates are at a constant increase. Tumourigenic cells are characteristically seen to over-express...
10.
Rebelo T, Vania L, Ferreira E, Weiss S
Exp Cell Res . 2018 Apr; 368(1):1-12. PMID: 29653110
Implications: siRNAs mediated LRP knock-down might represent a powerful alternative therapeutic strategy for the treatment of malignant melanoma through the induction of apoptosis.