Ellis J Neufeld
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Explore the profile of Ellis J Neufeld including associated specialties, affiliations and a list of published articles.
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130
Citations
2830
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Recent Articles
1.
Kim T, Geris J, Flanagan J, Grace R, Lambert M, OFarrell C, et al.
Blood Adv
. 2024 Aug;
8(21):5529-5538.
PMID: 39189922
Through the use of genetic sequencing, molecular variants driving autoimmunity are increasingly identified in patients with chronic and refractory immune cytopenias. With the goal of discovering genetic variants that predispose...
2.
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Al-Samkari H, Shehata N, Lang-Robertson K, Bianchi P, Glenthoj A, Sheth S, et al.
Lancet Haematol
. 2024 Feb;
11(3):e228-e239.
PMID: 38330977
Pyruvate kinase (PK) deficiency is the most common cause of chronic congenital non-spherocytic haemolytic anaemia worldwide, with an estimated prevalence of one in 100 000 to one in 300 000...
4.
Al-Samkari H, Neufeld E
Br J Haematol
. 2023 Sep;
203(1):65-78.
PMID: 37735554
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder affecting approximately 1 in 20 000 people. While most patients with ITP are successfully managed with the current set of standard and...
5.
Mathias M, Abraham A, Belletrutti M, Carcao M, Carvalho M, Chambost H, et al.
Eur J Haematol
. 2023 Jul;
111(4):544-552.
PMID: 37439123
Introduction: Simoctocog alfa (Nuwiq®) is a 4th generation recombinant FVIII with proven efficacy for the prevention and treatment of bleeding episodes (BEs) in previously treated patients with severe haemophilia A....
6.
Cappellini M, Taher A, Piga A, Shah F, Voskaridou E, Viprakasit V, et al.
Eur J Haematol
. 2023 Apr;
111(1):113-124.
PMID: 37095595
Background: Patients with transfusion-dependent (TD) β-thalassemia require long-term red blood cell transfusions (RBCTs) that lead to iron overload, impacting health-related quality of life (HRQoL). Methods: The impact of luspatercept, a...
7.
Ragni M, Young G, Batsuli G, Bisson E, Carpenter S, Croteau S, et al.
Expert Rev Hematol
. 2023 Mar;
16(sup1):107-127.
PMID: 36920855
Background: The National Hemophilia Foundation (NHF) conducted extensive, inclusive community consultations to guide prioritization of research in coming decades in alignment with its mission to find cures and address and...
8.
Bolous N, Bhatt N, Bhakta N, Neufeld E, Davidoff A, Reiss U
J Blood Med
. 2022 Oct;
13:559-580.
PMID: 36226233
Gene therapy for hemophilia using adeno-associated virus (AAV) derived vectors can reduce or eliminate patients' disease-related complications and improve their quality of life. Broad implementation globally will lead to societal...
9.
Chapin J, Cohen A, Neufeld E, Vichinsky E, Giardina P, Boudreaux J, et al.
Br J Haematol
. 2021 Nov;
196(2):380-389.
PMID: 34775608
Thalassaemia is caused by genetic globin defects leading to anaemia, transfusion-dependence and comorbidities. Reduced survival and systemic organ disease affect transfusion-dependent thalassaemia major and thalassaemia intermedia. Recent improvements in clinical...
10.
Shimano K, Grace R, Despotovic J, Neufeld E, Klaassen R, Bennett C, et al.
BMJ Open
. 2021 Aug;
11(8):e044885.
PMID: 34452956
Introduction: Immune thrombocytopaenia (ITP) is an acquired disorder of low platelets and risk of bleeding. Although many children can be observed until spontaneous remission, others require treatment due to bleeding...