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Elke Muth-Kohne

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Citations 112
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Muth-Kohne E, Westphal-Settele K, Bruckner J, Konradi S, Schiller V, Schafers C, et al.
Aquat Toxicol . 2016 May; 176:116-27. PMID: 27130971
The Fish Sexual Development Test (FSDT) is a non-reproductive test to assess adverse effects of endocrine disrupting chemicals. With the present study it was intended to evaluate whether gene expression...
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Sonnack L, Kampe S, Muth-Kohne E, Erdinger L, Henny N, Hollert H, et al.
Neurotoxicol Teratol . 2015 May; 50:33-42. PMID: 26006317
Low level metal contaminations are a prevalent issue with often unknown consequences for health and the environment. Effect-based, multifactorial test systems with zebrafish embryos to assess in particular developmental toxicity...
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Pachernegg S, Munster Y, Muth-Kohne E, Fuhrmann G, Hollmann M
Front Cell Neurosci . 2015 Mar; 9:69. PMID: 25798088
The majority of AMPA receptors in the adult brain contain GluA2 subunits, which can be edited at the Q/R site, changing a glutamine to an arginine within the ion pore....
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Delov V, Muth-Kohne E, Schafers C, Fenske M
Aquat Toxicol . 2014 Apr; 150:189-200. PMID: 24685623
The fish embryo toxicity test (FET) is currently one of the most advocated animal alternative tests in ecotoxicology. To date, the application of the FET with zebrafish (zFET) has focused...
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Pachernegg S, Joshi I, Muth-Kohne E, Pahl S, Munster Y, Terhag J, et al.
Front Cell Neurosci . 2013 Dec; 7:241. PMID: 24348335
Ionotropic glutamate receptors (iGluRs) do not only mediate the majority of excitatory neurotransmission in the vertebrate CNS, but also modulate pre- and postnatal neurogenesis. Most of the studies on the...
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Muth-Kohne E, Sonnack L, Schlich K, Hischen F, Baumgartner W, Hund-Rinke K, et al.
Ecotoxicology . 2013 Aug; 22(8):1264-77. PMID: 23975539
Silver nanoparticles (AgNPs) are widely believed to be retained in the sewage sludge during sewage treatment. The AgNPs and their derivatives, however, re-enter the environment with the sludge and via...
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Schiller V, Wichmann A, Kriehuber R, Muth-Kohne E, Giesy J, Hecker M, et al.
Comp Biochem Physiol C Toxicol Pharmacol . 2012 Sep; 157(1):41-53. PMID: 23017276
Assessment of endocrine disruption currently relies on testing strategies involving adult vertebrates. In order to minimize the use of animal tests according to the 3Rs principle of replacement, reduction and...
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Muth-Kohne E, Wichmann A, Delov V, Fenske M
Neurotoxicol Teratol . 2012 Jun; 34(4):413-24. PMID: 22729072
Rodents are widely used to test the developmental neurotoxicity potential of chemical substances. The regulatory test procedures are elaborate and the requirement of numerous animals is ethically disputable. Therefore, non-animal...
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Muth-Kohne E, Pachernegg S, Karus M, Faissner A, Hollmann M
Cell Physiol Biochem . 2011 Jan; 26(6):935-46. PMID: 21220924
Glutamate and its receptors are ascribed a pivotal role during acitivity-dependent neurogenesis. Nevertheless, their precise expression patterns during embryonic and adult differentiation remain elusive. An in vitro-approach that includes cells...