Elizabeth S Maywood
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Explore the profile of Elizabeth S Maywood including associated specialties, affiliations and a list of published articles.
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59
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Recent Articles
1.
Beale A, Hayter E, Crosby P, Valekunja U, Edgar R, Chesham J, et al.
EMBO J
. 2023 Aug;
42(19):e114164.
PMID: 37554073
Cellular circadian rhythms confer temporal organisation upon physiology that is fundamental to human health. Rhythms are present in red blood cells (RBCs), the most abundant cell type in the body,...
2.
McManus D, Polidarova L, Smyllie N, Patton A, Chesham J, Maywood E, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(34):e2203563119.
PMID: 35976881
The suprachiasmatic nucleus (SCN) of the hypothalamus is the principal clock driving circadian rhythms of physiology and behavior that adapt mammals to environmental cycles. Disruption of SCN-dependent rhythms compromises health,...
3.
Wilcox A, Bains R, Williams D, Joynson E, Vizor L, Oliver P, et al.
iScience
. 2021 Oct;
24(10):103142.
PMID: 34632336
Circadian rhythms persist in almost all organisms and are crucial for maintaining appropriate timing in physiology and behaviour. Here, we describe a mouse mutant where the central mammalian pacemaker, the...
4.
Maywood E, Chesham J, Winsky-Sommerer R, Hastings M
J Neurosci
. 2021 Aug;
41(41):8562-8576.
PMID: 34446572
The timing and quality of sleep-wake cycles are regulated by interacting circadian and homeostatic mechanisms. Although the suprachiasmatic nucleus (SCN) is the principal clock, circadian clocks are active across the...
5.
Hamnett R, Chesham J, Maywood E, Hastings M
J Neurosci
. 2020 Nov;
41(3):502-512.
PMID: 33234609
Circadian (approximately daily) rhythms pervade mammalian behavior. They are generated by cell-autonomous, transcriptional/translational feedback loops (TTFLs), active in all tissues. This distributed clock network is coordinated by the principal circadian...
6.
Patton A, Edwards M, Smyllie N, Hamnett R, Chesham J, Brancaccio M, et al.
Nat Commun
. 2020 Jul;
11(1):3394.
PMID: 32636383
The hypothalamic suprachiasmatic nuclei (SCN) are the principal mammalian circadian timekeeper, co-ordinating organism-wide daily and seasonal rhythms. To achieve this, cell-autonomous circadian timing by the ~20,000 SCN cells is welded...
7.
Crosby P, Hamnett R, Putker M, Hoyle N, Reed M, Karam C, et al.
Cell
. 2019 Apr;
177(4):896-909.e20.
PMID: 31030999
In mammals, endogenous circadian clocks sense and respond to daily feeding and lighting cues, adjusting internal ∼24 h rhythms to resonate with, and anticipate, external cycles of day and night....
8.
Hastings M, Maywood E, Brancaccio M
Biology (Basel)
. 2019 Mar;
8(1).
PMID: 30862123
The past twenty years have witnessed the most remarkable breakthroughs in our understanding of the molecular and cellular mechanisms that underpin circadian (approximately one day) time-keeping. Across model organisms in...
9.
Brancaccio M, Edwards M, Patton A, Smyllie N, Chesham J, Maywood E, et al.
Science
. 2019 Jan;
363(6423):187-192.
PMID: 30630934
Circadian (~24-hour) rhythms depend on intracellular transcription-translation negative feedback loops (TTFLs). How these self-sustained cellular clocks achieve multicellular integration and thereby direct daily rhythms of behavior in animals is largely...
10.
Maywood E, Elliott T, Patton A, Krogager T, Chesham J, Ernst R, et al.
Proc Natl Acad Sci U S A
. 2018 Nov;
115(52):E12388-E12397.
PMID: 30487216
The suprachiasmatic nucleus (SCN) is the principal circadian clock of mammals, coordinating daily rhythms of physiology and behavior. Circadian timing pivots around self-sustaining transcriptional-translational negative feedback loops (TTFLs), whereby CLOCK...