Elizabeth McMichael
Overview
Explore the profile of Elizabeth McMichael including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
369
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0
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Recent Articles
1.
Yang T, Ding X, McMichael E, Pun F, Aliper A, Ren F, et al.
J Cheminform
. 2024 Dec;
16(1):143.
PMID: 39716240
Cardiotoxicity, particularly drug-induced arrhythmias, poses a significant challenge in drug development, highlighting the importance of early-stage prediction of human ether-a-go-go-related gene (hERG) toxicity. hERG encodes the pore-forming subunit of the...
2.
Pinette A, McMichael E, Courtney N, Duggan M, Benner B, Choueiry F, et al.
Cancer Immunol Immunother
. 2019 Jul;
68(8):1379-1389.
PMID: 31338557
Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide and epidermal growth factor receptor (EGFR) is overexpressed in greater than 90% of patient...
3.
Mace T, Ware M, King S, Loftus S, Farren M, McMichael E, et al.
Sci Rep
. 2019 Mar;
9(1):5068.
PMID: 30911044
Soybeans are a rich source of isoflavones that have been linked with anti-inflammatory processes and various health benefits. However, specific mechanisms whereby soy bioactives impact immune cell subsets are unclear....
4.
Hu Z, Shen R, Campbell A, McMichael E, Yu L, Ramaswamy B, et al.
Cancer Immunol Res
. 2018 Apr;
6(6):671-684.
PMID: 29622581
Triple-negative breast cancer (TNBC) is a leading cause of breast cancer death and is often associated with and mutation. Due to the lack of validated target molecules, no targeted therapy...
5.
Stiff A, Trikha P, Mundy-Bosse B, McMichael E, Mace T, Benner B, et al.
Clin Cancer Res
. 2018 Jan;
24(8):1891-1904.
PMID: 29363526
mAbs are used to treat solid and hematologic malignancies and work in part through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of NK cells from patients...
6.
Hu Z, Xu J, Cheng J, McMichael E, Yu L, Carson 3rd W
Oncotarget
. 2016 Dec;
8(1):1481-1494.
PMID: 27903969
Targeting cancer stem cell (CSC) represents a promising therapeutic approach as it can potentially fight cancer at its root. The challenge is to identify a surface therapeutic oncotarget on CSC....
7.
Stiff A, Trikha P, Wesolowski R, Kendra K, Hsu V, Uppati S, et al.
Cancer Res
. 2016 Feb;
76(8):2125-36.
PMID: 26880800
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immature myeloid cells that expand in tumor-bearing hosts in response to soluble factors produced by tumor and stromal cells. MDSC expansion...
8.
Jaime-Ramirez A, McMichael E, Kondadasula S, Skinner C, Mundy-Bosse B, Luedke E, et al.
Cancer Immunol Res
. 2016 Feb;
4(4):323-336.
PMID: 26865456
Optimally effective antitumor therapies would not only activate immune effector cells but also engage them at the tumor. Folate conjugated to immunoglobulin (F-IgG) could direct innate immune cells with Fc...
9.
Rauzan B, McMichael E, Cave R, Sevcik L, Ostrosky K, Whitman E, et al.
Biochemistry
. 2013 Jan;
52(5):765-72.
PMID: 23356429
The rates of duplex formation for two octamers of DNA (5' d-CACGGCTC/5' d-GAGCCGTG and 5' d-CACAGCAC/5' d-GTGCTGTG), the homologous RNA, and both sets of hybrids in 1 M NaCl buffer...