Elizabeth H Nardin
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Explore the profile of Elizabeth H Nardin including associated specialties, affiliations and a list of published articles.
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11
Citations
265
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Recent Articles
1.
Mitchell R, Altszuler R, Frevert U, Nardin E
Sci Rep
. 2016 Sep;
6:32575.
PMID: 27624667
Malaria eradication will require a combination of vector control, chemotherapy and an easily administered vaccine. Sterile immunity can be elicited in humans by immunization with sporozoites, the infective stage injected...
2.
Zhang M, Kaneko I, Tsao T, Mitchell R, Nardin E, Iwanaga S, et al.
Malar J
. 2016 Apr;
15:201.
PMID: 27068454
Background: Plasmodium circumsporozoite protein (CSP) is a major surface antigen present in the sporozoite (Spz) stage of a malaria parasite. RTS, S vaccine, the most clinically advanced malaria vaccine, consists...
3.
Huang J, Li X, Coelho-Dos-Reis J, Zhang M, Mitchell R, Nogueira R, et al.
J Immunol Methods
. 2015 Sep;
427:42-50.
PMID: 26410104
In this study, we developed human immune system (HIS) mice that possess functional human CD4+ T cells and B cells, named HIS-CD4/B mice. HIS-CD4/B mice were generated by first introducing...
4.
Rudra J, Mishra S, Chong A, Mitchell R, Nardin E, Nussenzweig V, et al.
Biomaterials
. 2012 Jun;
33(27):6476-84.
PMID: 22695068
Biomaterials that modulate innate and adaptive immune responses are receiving increasing interest as adjuvants for eliciting protective immunity against a variety of diseases. Previous results have indicated that self-assembling β-sheet...
5.
Oliveira G, Kumar K, Calvo-Calle J, Othoro C, Altszuler D, Nussenzweig V, et al.
Infect Immun
. 2007 Dec;
76(3):1200-6.
PMID: 18160479
The irradiated-sporozoite vaccine elicits sterile immunity against Plasmodium parasites in experimental rodent hosts and human volunteers. Based on rodent malaria models, it has been proposed that CD8+ T cells are...
6.
Calvo-Calle J, Oliveira G, Watta C, Soverow J, Parra-Lopez C, Nardin E
Infect Immun
. 2006 Oct;
74(12):6929-39.
PMID: 17030584
An effective malaria vaccine is needed to address the public health tragedy resulting from the high levels of morbidity and mortality caused by Plasmodium parasites. The first protective immune mechanism...
7.
Calvo-Calle J, Oliveira G, Nardin E
J Immunol
. 2005 Nov;
175(11):7575-85.
PMID: 16301667
Peptide vaccines containing minimal epitopes of protective Ags provide the advantages of low cost, safety, and stability while focusing host responses on relevant targets of protective immunity. However, the limited...
8.
Oliveira G, Wetzel K, Calvo-Calle J, Nussenzweig R, Schmidt A, Birkett A, et al.
Infect Immun
. 2005 May;
73(6):3587-97.
PMID: 15908388
Highly purified subunit vaccines require potent adjuvants in order to elicit optimal immune responses. In a previous phase I trial, an alum formulation of ICC-1132, a malaria vaccine candidate comprising...
9.
Nardin E, Oliveira G, Calvo-Calle J, Wetzel K, Maier C, Birkett A, et al.
Infect Immun
. 2004 Oct;
72(11):6519-27.
PMID: 15501783
We report the first phase I trial to assess the safety and immunogenicity of a malaria vaccine candidate, ICC-1132 (Malarivax), composed of a modified hepatitis B virus core protein (HBc)...
10.
Edelman R, Wasserman S, Kublin J, Bodison S, Nardin E, Oliveira G, et al.
Vaccine
. 2002 Nov;
21(3-4):269-80.
PMID: 12450702
We tested the clinical reactions to a synthetic, Plasmodium falciparum, circumsporozoite multiple antigen peptide (MAP) vaccine in 39 volunteers immunized two to three times over 2-8 months using a dose...