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Elizabeth Bernstein

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Articles 22
Citations 185
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Recent Articles
11.
Kennedy G, Azari F, Bernstein E, Nadeem B, Chang A, Segil A, et al.
Nat Commun . 2022 May; 13(1):2711. PMID: 35581212
Suspicious nodules detected by radiography are often investigated by biopsy, but the diagnostic yield of biopsies of small nodules is poor. Here we report a method-NIR-nCLE-to detect cancer at the...
12.
Azari F, Kennedy G, Zhang K, Bernstein E, Maki R, Gaughan C, et al.
J Am Coll Surg . 2022 Apr; 234(5):748-758. PMID: 35426386
Background: Intraoperative molecular imaging (IMI) has been shown to improve lesion detection during pulmonary sarcomatous metastasectomy. Our goal in this study was to evaluate whether data garnered from IMI-guided resection...
13.
Azari F, Kennedy G, Zhang K, Bernstein E, Chang A, Nadeem B, et al.
Mol Imaging Biol . 2022 Mar; 25(1):156-167. PMID: 35290565
Background: One of the novel advancements to enhance the visual aspects of lung cancer identification is intraoperative molecular imaging (IMI), which can reliably detect tumors that would otherwise be missed...
14.
Kennedy G, Azari F, Bernstein E, Nadeem B, Chang A, Segil A, et al.
Mol Cancer Ther . 2022 Feb; 21(4):546-554. PMID: 35149546
Pulmonary squamous cell carcinoma is the second most common lung cancer subtype and has a low 5-year survival rate at 17.6%. Complete resection with negative margins can be curative, but...
15.
Kennedy G, Azari F, Bernstein E, Desphande C, Din A, Marfatia I, et al.
Ann Thorac Surg . 2021 Nov; 114(6):2115-2123. PMID: 34774493
Background: Pulmonary ground glass opacities (GGOs) are early-stage adenocarcinoma spectrum lesions that are not easily palpable. Challenges in localizing GGOs during intraoperative pathology can lead to imprecise diagnoses and additional...
16.
Kennedy G, Azari F, Bernstein E, Marfatia I, Din A, Kucharczuk J, et al.
JAMA Surg . 2021 Aug; 156(11):1043-1050. PMID: 34431971
Importance: Complete (R0) resection is the dominant prognostic factor for survival across solid tumor types. Achieving adequate tumor clearance with appropriate margins is particularly difficult in nonpalpable tumors or in...
17.
Azari F, Kennedy G, Bernstein E, Delikatny J, Lee J, Kucharczuk J, et al.
Mol Imaging Biol . 2021 Jun; 25(1):85-96. PMID: 34101106
Introduction: Cancer surgery has multiple challenges including localizing small lesions, ensuring negative margins, and identifying synchronous cancers. One of the tools proposed to address these issues is intraoperative molecular imaging...
18.
Azari F, Kennedy G, Bernstein E, Hadjipanayis C, Vahrmeijer A, Smith B, et al.
J Biomed Opt . 2021 May; 26(5). PMID: 34002555
Significance: Surgery is often paramount in the management of many solid organ malignancies because optimal resection is a major factor in disease-specific survival. Cancer surgery has multiple challenges including localizing...
19.
Highfill T, Bernstein E
Int J Health Econ Manag . 2019 Apr; 19(3-4):449-466. PMID: 30963361
Health care spending in the U.S. grew two trillion dollars from 1987 to 2010, a 400% increase, but our understanding of the value of that increase is limited. In this...
20.
Albayram O, Angeli P, Bernstein E, Baxley S, Gao Z, Lu K, et al.
J Alzheimers Dis Parkinsonism . 2018 Sep; 8(3). PMID: 30197831
Tau is a microtubule-associated protein heavily implicated in neurodegenerative diseases collectively known as tauopathies, including Alzheimer's disease and chronic traumatic encephalopathy. Phosphorylation of tau at Thr231 allows for the isomerization...