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Elham Pourmand

Explore the profile of Elham Pourmand including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 22
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Recent Articles
1.
McDonald O, Wagner J, Lewandowski R, Heine L, Estrada V, Pourmand E, et al.
Inhal Toxicol . 2024 Oct; 36(7-8):442-460. PMID: 39418113
Objective: Acute intranasal (IN) instillation of lupus-prone NZBWF1 mice with crystalline silica (cSiO) triggers robust lung inflammation that drives autoimmunity. Prior studies in other preclinical models show that soluble epoxide...
2.
Sarparast M, Hinman J, Pourmand E, Vonarx D, Ramirez L, Ma W, et al.
bioRxiv . 2023 Oct; PMID: 37873467
This study aims to uncover potent cytochrome P450 (CYP) and epoxide hydrolase (EH) metabolites implicated in Aβ and/or tau-induced neurodegeneration, independent of neuroinflammation, by utilizing () as a model organism....
3.
Pourmand E, Zhang F, Sarparast M, Alan J, Lee K
bioRxiv . 2023 Oct; PMID: 37873260
Aging is one of the major risk factors for many chronic diseases, including diabetes, neuropathy, hypertension, cancer, and neurodegenerative diseases. However, the mechanism behind aging and how aging affects a...
4.
Zhang J, Yang J, Duval C, Edin M, Williams A, Lei L, et al.
FASEB J . 2023 Jun; 37(7):e23009. PMID: 37273180
Human and animal studies support that consuming a high level of linoleic acid (LA, 18:2ω-6), an essential fatty acid and key component of the human diet, increases the risk of...
5.
Sarparast M, Pourmand E, Hinman J, Vonarx D, Reason T, Zhang F, et al.
ACS Cent Sci . 2023 May; 9(5):870-882. PMID: 37252355
Even after decades of research, the mechanism of neurodegeneration remains understudied, hindering the discovery of effective treatments for neurodegenerative diseases. Recent reports suggest that ferroptosis could be a novel therapeutic...
6.
Favor O, Chauhan P, Pourmand E, Edwards A, Wagner J, Lewandowski R, et al.
Front Immunol . 2023 Mar; 14:1124910. PMID: 36875087
Introduction: Lipopolysaccharide (LPS)-accelerated autoimmune glomerulonephritis (GN) in NZBWF1 mice is a preclinical model potentially applicable for investigating lipidome-modulating interventions against lupus. LPS can be expressed as one of two chemotypes:...
7.
Sarparast M, Pourmand E, Hinman J, Vonarx D, Reason T, Zhang F, et al.
bioRxiv . 2023 Jan; PMID: 36711920
Even after decades of research, the mechanism of neurodegeneration remains understudied, hindering the discovery of effective treatments for neurodegenerative diseases. Recent reports suggest that ferroptosis could be a novel therapeutic...