Elena Shersher
Overview
Explore the profile of Elena Shersher including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
28
Followers
0
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Recent Articles
1.
Diluvio G, Kelley T, Lahiry M, Alvarez-Trotta A, Kolb E, Shersher E, et al.
Mol Ther Oncolytics
. 2023 Mar;
28:307-320.
PMID: 36938545
Notch activation complex kinase (NACK) is a component of the Notch transcriptional machinery critical for the Notch-mediated tumorigenesis. However, the mechanism through which NACK regulates Notch-mediated transcription is not well...
2.
Shersher E, Lahiry M, Alvarez-Trotta A, Diluvio G, Robbins D, Shiekhattar R, et al.
Cell Commun Signal
. 2021 Sep;
19(1):96.
PMID: 34551776
Background: Notch signaling drives many aspects of neoplastic phenotype. Here, we report that the Integrator complex (INT) is a new component of the Notch transcriptional supercomplex. Together with Notch Activation...
3.
Alvarez-Trotta A, Guerrant W, Astudillo L, Lahiry M, Diluvio G, Shersher E, et al.
Cancer Res
. 2021 Apr;
81(12):3347-3357.
PMID: 33820800
In many human cancers, deregulation of the Notch pathway has been shown to play a role in the initiation and maintenance of the neoplastic phenotype. Aberrant Notch activity also plays...
4.
Alvarez-Trotta A, Wang Z, Shersher E, Li B, Long J, Lohse I, et al.
Oncotarget
. 2020 Sep;
11(33):3174-3187.
PMID: 32913560
The Hedgehog/GLI (HH/GLI) signaling pathway plays a critical role in human oncogenesis. Unfortunately, the clinical use of HH inhibitor(s) has been associated with serious adverse effects and mutation-related drug resistance....