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Elena Casiraghi

Explore the profile of Elena Casiraghi including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 547
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Recent Articles
1.
Gliozzo J, Soto-Gomez M, Guarino V, Bonometti A, Cabri A, Cavalleri E, et al.
Artif Intell Med . 2024 Dec; 160():103049. PMID: 39673960
Multi-omics data have revolutionized biomedical research by providing a comprehensive understanding of biological systems and the molecular mechanisms of disease development. However, analyzing multi-omics data is challenging due to high...
2.
Daveri E, Vergani B, Lalli L, Ferrero G, Casiraghi E, Cova A, et al.
J Immunother Cancer . 2024 Oct; 12(10). PMID: 39395839
Background: Colorectal cancer (CRC) remains a significant healthcare burden worldwide, characterized by a complex interplay between obesity and chronic inflammation. While the relationship between CRC, obesity and altered lipid metabolism...
3.
Righetti S, Medoro A, Graziano F, Mondazzi L, Martegani S, Chiappero F, et al.
Nutrients . 2024 Sep; 16(18). PMID: 39339678
Background: Managing metabolism for optimal training, performance, and recovery in medium-to-high-level endurance runners involves enhancing energy systems through strategic nutrient intake. Optimal carbohydrate intake before, during, and after endurance running...
4.
Li A, Casiraghi E, Rousu J
Bioinformatics . 2024 Sep; 40(10). PMID: 39271156
Motivation: Molecular representation learning (MRL) models molecules with low-dimensional vectors to support biological and chemical applications. Current methods primarily rely on intrinsic molecular information to learn molecular representations, but they...
5.
Niyonkuru E, Caufield J, Carmody L, Gargano M, Toro S, Whetzel P, et al.
medRxiv . 2024 Sep; PMID: 39228707
Structured representations of clinical data can support computational analysis of individuals and cohorts, and ontologies representing disease entities and phenotypic abnormalities are now commonly used for translational research. The Medical...
6.
Cavalleri E, Cabri A, Soto-Gomez M, Bonfitto S, Perlasca P, Gliozzo J, et al.
Sci Data . 2024 Aug; 11(1):906. PMID: 39174566
The "RNA world" represents a novel frontier for the study of fundamental biological processes and human diseases and is paving the way for the development of new drugs tailored to...
7.
Reese J, Chimirri L, Bridges Y, Danis D, Caufield J, Wissink K, et al.
medRxiv . 2024 Aug; PMID: 39108510
Large language models (LLMs) show promise in supporting differential diagnosis, but their performance is challenging to evaluate due to the unstructured nature of their responses. To assess the current capabilities...
8.
Pasquali S, Vallacchi V, Lalli L, Collini P, Barisella M, Romagosa C, et al.
EBioMedicine . 2024 Jul; 106:105220. PMID: 39018755
Background: Anthracycline-based neoadjuvant chemotherapy (NAC) may modify tumour immune infiltrate. This study characterized immune infiltrate spatial distribution after NAC in primary high-risk soft tissue sarcomas (STS) and investigate association with...
9.
Niyonkuru E, Gomez M, Casiraghi E, Antogiovanni S, Blau H, Reese J, et al.
bioRxiv . 2024 Jul; PMID: 39005436
Objectives: Concept embeddings are low-dimensional vector representations of concepts such as MeSH:D009203 (Myocardial Infarction), whose similarity in the embedded vector space reflects their semantic similarity. Here, we test the hypothesis...
10.
Coleman B, Casiraghi E, Callahan T, Blau H, Chan L, Laraway B, et al.
Transl Psychiatry . 2024 Jun; 14(1):246. PMID: 38851761
Acute COVID-19 infection can be followed by diverse clinical manifestations referred to as Post Acute Sequelae of SARS-CoV2 Infection (PASC). Studies have shown an increased risk of being diagnosed with...