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Elena Alexandrova

Explore the profile of Elena Alexandrova including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 320
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Recent Articles
1.
Alexandrova E, Smal M, Di Rosa D, Brancaccio R, Parisi R, Russo F, et al.
Sci Rep . 2025 Mar; 15(1):7602. PMID: 40038391
Ovarian Cancer (OC) is the most lethal gynecological malignancy, characterized by peritoneal metastasis, directly linked to most OC-related deaths. Here, by interrogating CRISPR-Cas9 loss-of-function genetic screen data, we identified a...
2.
Garcia-Martinez Y, Alexandrova E, Iebba V, Ferravante C, Spinelli M, Franci G, et al.
BMC Microbiol . 2024 Oct; 24(1):436. PMID: 39462312
Background: Chronic Kidney Disease (CKD) is characterized by a methionine-related metabolic disorder involving reduced plasma levels of hydrogen sulfide (HS) and increased lanthionine. The gut microbiota influences methionine metabolism, potentially...
3.
Smal M, Memoli D, Alexandrova E, Di Rosa D, DAgostino Y, Russo F, et al.
Sci Data . 2024 Jul; 11(1):767. PMID: 38997254
Small non-coding RNAs (sncRNAs) make up ~1% of the transcriptome; nevertheless, they play significant roles in regulating cellular processes. Given the complexity of the central nervous system, sncRNAs likely hold...
4.
Pannetta M, Smal M, Ferravante C, Eletto D, Di Rosa D, Alexandrova E, et al.
Diagn Microbiol Infect Dis . 2024 Jun; 110(1):116401. PMID: 38878343
Brucellosis is a critical zoonotic disease impacting humans and animals globally, causing symptoms like fever and arthritis in humans and reproductive issues in animals. The disease stems from the Brucella...
5.
Ronchi S, Facchi S, Di Lauro E, Libera L, Carnevali I, Zefiro F, et al.
Pathol Res Pract . 2024 Feb; 255:155183. PMID: 38364651
Epithelial ovarian cancers (EOC) associated with germline or somatic BRCA pathogenetic variants have a significantly higher rate of TP53aberrations. The majority of TP53 mutations are detectable by immunohistochemistry and several...
6.
Salvati A, Ferravante C, Lamberti J, Rocco T, Alexandrova E, DAgostino Y, et al.
Sci Data . 2023 Sep; 10(1):588. PMID: 37679338
No abstract available.
7.
Salvati A, Ferravante C, Lamberti J, Rocco T, Alexandrova E, DAgostino Y, et al.
Sci Data . 2023 Jun; 10(1):379. PMID: 37316506
The ongoing COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people worldwide and has significant implications for public health. Host transcriptomics profiling provides comprehensive understanding of how the virus...
8.
Melone V, Salvati A, Brusco N, Alexandrova E, DAgostino Y, Palumbo D, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674656
In the complex and articulated machinery of the human genome, less than 2% of the transcriptome encodes for proteins, while at least 75% is actively transcribed into non-coding RNAs (ncRNAs)....
9.
Alexandrova E, Lamberti J, Memoli D, Quercia C, Melone V, Rizzo F, et al.
Cancer Cell Int . 2022 Nov; 22(1):336. PMID: 36333801
Background: Ovarian cancer (OC) is characterized by a low response rate and high frequency of resistance development to currently available treatments. The therapeutic potential of histone methyltransferase DOT1L inhibitor in...
10.
DAgostino Y, Palumbo D, Rusciano M, Strianese O, Amabile S, Di Rosa D, et al.
Diagnostics (Basel) . 2022 Oct; 12(10). PMID: 36292100
Dilated cardiomyopathy (DCM) is a complex disease affecting young adults. It is a pathological condition impairing myocardium activity that leads to heart failure and, in the most severe cases, transplantation,...