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Elda Chiaino

Explore the profile of Elda Chiaino including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 38
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Recent Articles
1.
Pifferi A, Chiaino E, Fernandez-Abascal J, Bannon A, Davey G, Frosini M, et al.
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000543
Human individual differences in brain cytochrome P450 (CYP) metabolism, including induction, inhibition, and genetic variation, may influence brain sensitivity to neurotoxins and thus participate in the onset of neurodegenerative diseases....
2.
Durante M, Frosini M, Chiaino E, Fusi F, Gamberucci A, Gorelli B, et al.
Vascul Pharmacol . 2022 Feb; 143:106969. PMID: 35149209
Sdox is a synthetic HS-releasing doxorubicin (Dox) less cardiotoxic and more effective than Dox in pre-clinical, Dox-resistant tumour models. The well-known anthracycline vascular toxicity, however, might limit Sdox clinical use....
3.
Chiaino E, Stella R, Peggion C, Micucci M, Budriesi R, Mattioli L, et al.
Antioxidants (Basel) . 2022 Jan; 11(1). PMID: 35052585
Oxidative stress (OS) and the resulting reactive oxygen species (ROS) generation and inflammation play a pivotal role in the neuronal loss occurring during the onset of neurodegenerative diseases. Therefore, promising...
4.
Chiaino E, Micucci M, Budriesi R, Mattioli L, Marzetti C, Corsini M, et al.
Antioxidants (Basel) . 2021 Dec; 10(12). PMID: 34943065
Compounds of natural origin may constitute an interesting tool for the treatment of neuroblastoma, the most prevalent extracranial solid tumor in children. PRES is a commercially available food supplement, composed...
5.
Chiaino E, Micucci M, Cosconati S, Novellino E, Budriesi R, Chiarini A, et al.
Antioxidants (Basel) . 2020 Sep; 9(9). PMID: 32882797
Oxidative stress (OS) arising from tissue redox imbalance, critically contributes to the development of neurodegenerative disorders. Thus, natural compounds, owing to their antioxidant properties, have promising therapeutic potential. (PRES) is...
6.
Fernandez-Abascal J, Chiaino E, Frosini M, Davey G, Valoti M
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32486438
The 1-methyl-4-phenylpyridinium (MPP) is a parkinsonian-inducing toxin that promotes neurodegeneration of dopaminergic cells by directly targeting complex I of mitochondria. Recently, it was reported that some Cytochrome P450 (CYP) isoforms,...
7.
Chiaino E, Micucci M, Durante M, Budriesi R, Gotti R, Marzetti C, et al.
Int J Mol Sci . 2020 Mar; 21(6). PMID: 32204339
The research for innovative treatments against colon adenocarcinomas is still a great challenge. Willd. heartwood extract (AC) has health-promoting qualities, especially at the gastrointestinal level. This study characterized AC for...