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Elaine E L Wang

Explore the profile of Elaine E L Wang including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 415
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Recent Articles
1.
Kraft C, Sims M, Silverman M, Louie T, Feuerstadt P, Huang E, et al.
Infect Dis Ther . 2024 Aug; 13(10):2209-2210. PMID: 39212853
No abstract available.
2.
Kraft C, Sims M, Silverman M, Louie T, Feuerstadt P, Huang E, et al.
Infect Dis Ther . 2024 Jun; 13(10):2105-2121. PMID: 38941068
Introduction: Recurrent Clostridioides difficile infection (rCDI) often occurs after standard-of-care antibiotics. VOWST oral spores (VOS, previously SER-109), an FDA-approved orally administered microbiome therapeutic, is indicated to prevent rCDI following antibiotics...
3.
Berenson C, Lashner B, Korman L, Hohmann E, Deshpande A, Louie T, et al.
Clin Infect Dis . 2023 Aug; 77(11):1504-1510. PMID: 37539715
Background: Although comorbidities are risk factors for recurrent Clostridioides difficile infection (rCDI), many clinical trials exclude patients with medical conditions such as malignancy or immunosuppression. In a phase 3, double-blind,...
4.
Sims M, Khanna S, Feuerstadt P, Louie T, Kelly C, Huang E, et al.
JAMA Netw Open . 2023 Feb; 6(2):e2255758. PMID: 36780159
Importance: A safe and effective treatment for recurrent Clostridioides difficile infection (CDI) is urgently needed. Antibiotics kill toxin-producing bacteria but do not repair the disrupted microbiome, which promotes spore germination...
5.
Cohen S, Louie T, Sims M, Wang E, Memisoglu A, McGovern B, et al.
JAMA . 2022 Oct; 328(20):2062-2064. PMID: 36260754
No abstract available.
6.
Khanna S, Sims M, Louie T, Fischer M, LaPlante K, Allegretti J, et al.
Antibiotics (Basel) . 2022 Sep; 11(9). PMID: 36140013
Clostridioides difficile infection (CDI) is classified as an urgent health threat by the Centers for Disease Control and Prevention (CDC), and affects nearly 500,000 Americans annually. Approximately 20−25% of patients...
7.
Feuerstadt P, Louie T, Lashner B, Wang E, Diao L, Bryant J, et al.
N Engl J Med . 2022 Jan; 386(3):220-229. PMID: 35045228
Background: Current therapies for recurrent infection do not address the disrupted microbiome, which supports spore germination into toxin-producing bacteria. SER-109 is an investigational microbiome therapeutic composed of purified Firmicutes spores...
8.
Krueger J, Ferris L, Menter A, Wagner F, White A, Visvanathan S, et al.
J Allergy Clin Immunol . 2015 Mar; 136(1):116-124.e7. PMID: 25769911
Background: IL-23 is associated with plaque psoriasis susceptibility and pathogenesis. BI 655066 is a fully human IgG1 mAb specific for the IL-23 p19 subunit. Objective: This first-in-human proof-of-concept study evaluated...
9.
Shaikh N, Wang E, Arguedas A, Dagan R, Soley C, Song J, et al.
Pediatr Infect Dis J . 2011 Jan; 30(3):253-5. PMID: 21217538
We followed symptoms of children with acute otitis media (AOM), who were enrolled in a clinical trial that included a baseline tympanocentesis. We observed marked and rapid improvement in symptom...
10.
Wright J, Wang E, Owen J, Stephens D, Graham H, Hanlon M, et al.
Lancet . 2005 Mar; 365(9465):1153-8. PMID: 15794970
Background: Treatments for femoral fractures in children vary widely and have been investigated only in case series. We did a multicentre randomised trial to compare malunion rates after external fixation...