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El Cherif Ibrahim

Explore the profile of El Cherif Ibrahim including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 633
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Recent Articles
1.
Mokhtari A, Ibrahim E, Gloaguen A, Barrot C, Cohen D, Derouin M, et al.
EBioMedicine . 2025 Feb; 113:105569. PMID: 39914267
Background: Major depressive disorder (MDD) is a leading cause of disability, with a twofold increase in prevalence in women compared to men. Over the last few years, identifying molecular biomarkers...
2.
Lion M, Ibrahim E, Caccomo-Garcia E, Bourret J, Cinquanta G, Khalfallah O, et al.
Eur Neuropsychopharmacol . 2025 Jan; 93:5-14. PMID: 39874727
Major Depressive Episode (MDE) is one of the most common psychiatric disorders. Often difficult to treat, this disease is one of the leading causes of suicide. A recent study showed...
3.
Lin R, Mitsuhashi H, Fiori L, Denniston R, Ibrahim E, Belzung C, et al.
Sci Rep . 2024 Apr; 14(1):8258. PMID: 38589409
Major depressive disorder (MDD) is a complex and potentially debilitating illness whose etiology and pathology remains unclear. Non-coding RNAs have been implicated in MDD, where they display differential expression in...
4.
Fiorito A, Fakra E, Sescousse G, Ibrahim E, Rey R
Transl Psychiatry . 2023 Dec; 13(1):386. PMID: 38092734
Besides playing a central role in neuroinflammation, microglia regulate synaptic development and is involved in plasticity. Converging lines of evidence suggest that these different processes play a critical role in...
5.
Bourdon C, Etain B, Spano L, Belzeaux R, Leboyer M, Delahaye-Duriez A, et al.
Psychiatry Res . 2023 Aug; 327:115373. PMID: 37542794
Bipolar disorder (BD) is a chronic and severe psychiatric disorder associated with significant medical morbidity and reduced life expectancy. In this study, we assessed accelerated epigenetic aging in individuals with...
6.
Lin R, Kos A, Lopez J, Dine J, Fiori L, Yang J, et al.
Elife . 2023 Jul; 12. PMID: 37432876
Pharmacotherapies for the treatment of major depressive disorder were serendipitously discovered almost seven decades ago. From this discovery, scientists pinpointed the monoaminergic system as the primary target associated with symptom...
7.
Becker L, Fillinger C, Waegaert R, Journee S, Hener P, Ayazgok B, et al.
Nat Commun . 2023 Apr; 14(1):2198. PMID: 37069164
While depression and chronic pain are frequently comorbid, underlying neuronal circuits and their psychopathological relevance remain poorly defined. Here we show in mice that hyperactivity of the neuronal pathway linking...
8.
Ibrahim E, Gorgievski V, Ortiz-Teba P, Belzeaux R, Turecki G, Sibille E, et al.
Int J Mol Sci . 2022 Nov; 23(21). PMID: 36362329
Antidepressants (ADs) are, for now, the best everyday treatment we have for moderate to severe major depressive episodes (MDEs). ADs are among the most prescribed drugs in the Western Hemisphere;...
9.
Mokhtari A, Porte B, Belzeaux R, Etain B, Ibrahim E, Marie-Claire C, et al.
Prog Neuropsychopharmacol Biol Psychiatry . 2022 Feb; 116:110520. PMID: 35104608
Next-generation sequencing now enables the rapid and affordable production of reliable biological data at multiple molecular levels, collectively referred to as "omics". To maximize the potential for discovery, computational biologists...
10.
Penninck L, Ibrahim E, Artiges E, Gorgievski V, Desrivieres S, Farley S, et al.
Front Syst Neurosci . 2021 Oct; 15:725413. PMID: 34658802
Adolescence is a period of vulnerability for the maturation of gray matter (GM) and also for the onset of psychiatric disorders such as major depressive disorder (MDD), bipolar disorder and...