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Ekram Alias

Explore the profile of Ekram Alias including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 262
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Recent Articles
1.
Yee M, Chin K, Ima-Nirwana S, Alias E, Chua K, Wong S
Int J Med Sci . 2025 Feb; 22(3):585-603. PMID: 39898246
Carotene exists naturally in a complex mixture consisting of alpha (α), beta (β), and gamma (γ)-isoforms. Previous studies investigated the effects of individual carotene isomers on bone rather than their...
2.
Mohd Zaffarin A, Ng S, Ng M, Hassan H, Alias E
Pharmaceutics . 2025 Jan; 17(1). PMID: 39861662
: The tocotrienol-rich fraction (TRF) is a lipid-soluble vitamin that has good antioxidant and anti-inflammatory properties. The TRF is widely studied as a potential treatment for various diseases, including bone...
3.
Norazman S, Mohd Zaffarin A, Shuid A, Hassan H, Soleiman I, Kuan W, et al.
Int J Mol Sci . 2024 Sep; 25(17). PMID: 39273348
Preclinical research on diabetes and obesity has been carried out in various animal models over the years. These animal models are developed from genetic manipulation that affects their body metabolism,...
4.
Elahmer N, Wong S, Mohamed N, Alias E, Chin K, Muhammad N
Biomedicines . 2024 Aug; 12(8). PMID: 39200100
Osteoporosis, a metabolic bone disorder characterized by decreased bone mass per unit volume, poses a significant global health burden due to its association with heightened fracture risk and adverse impacts...
5.
Jayashankar S, Nasaruddin M, Hassan M, Dasrilsyah R, Shafiee M, Ismail N, et al.
Diagnostics (Basel) . 2023 Aug; 13(15). PMID: 37568933
Non-invasive prenatal testing was first discovered in 1988; it was primarily thought to be able to detect common aneuploidies, such as Patau syndrome (T13), Edward Syndrome (T18), and Down syndrome...
6.
Subramaniam R, Vijakumaran U, Shanmuganantha L, Law J, Alias E, Ng M
Int J Mol Sci . 2023 Jul; 24(14). PMID: 37511090
MicroRNAs are short, single-stranded ribonucleic acids expressed endogenously in the body to regulate gene expression at the post-translational level, with exogenous microRNA offering an attractive approach to therapy. Among the...
7.
Davan I, Fakurazi S, Alias E, Ibrahim N, Hwei N, Hassan H
Antioxidants (Basel) . 2023 Jul; 12(7). PMID: 37508018
In recent years, bone loss and its associated diseases have become a significant public health concern due to increased disability, morbidity, and mortality. Oxidative stress and bone loss are correlated,...
8.
Abdol Wahab N, Meor Mohd Affandi M, Fakurazi S, Alias E, Hassan H
Antioxidants (Basel) . 2022 Sep; 11(9). PMID: 36139750
Astaxanthin (3,3'-dihydroxy-4,4'-diketo-β-β carotene), which belongs to the xanthophyll class, has shown potential biological activity in in vitro and in vivo models including as a potent antioxidant, anti-lipid peroxidation and cardiovascular...
9.
Mohamad Hazir N, Mohamad Yahaya N, Zawawi M, Damanhuri H, Mohamed N, Alias E
Int J Mol Sci . 2022 Aug; 23(15). PMID: 35955464
Changes in mitochondrial bioenergetics are believed to take place during osteoclastogenesis. This study aims to assess changes in mitochondrial bioenergetics and reactive oxygen species (ROS) levels during polyethylene (PE)-induced osteoclastogenesis...
10.
Mohd Zaffarin A, Ng S, Ng M, Hassan H, Alias E
Nanomaterials (Basel) . 2021 Oct; 11(10). PMID: 34685010
Nano-hydroxyapatite (nHA) has been widely used as an orthopedic biomaterial and vehicle for drug delivery owing to its chemical and structural similarity to bone minerals. Several studies have demonstrated that...