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Eirini Pantazi

Explore the profile of Eirini Pantazi including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 857
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Recent Articles
1.
Reinke S, Pantazi E, Chappell G, Sanchez-Martinez A, Guyon R, Fergusson J, et al.
Cell Rep Med . 2023 Nov; 4(11):101245. PMID: 37913775
Adjuvanted protein vaccines offer high efficacy, yet most potent adjuvants remain proprietary. Several adjuvant compounds are being developed by the Vaccine Formulation Institute in Switzerland for global open access clinical...
2.
Ogbechi J, Wright H, Balint S, Topping L, Kristina Z, Huang Y, et al.
J Autoimmun . 2023 May; 138:103031. PMID: 37229811
The aim of this study was to assess the L-type amino acid transporter-1 (LAT1) as a possible therapeutic target for rheumatoid arthritis (RA). Synovial LAT1 expression in RA was monitored...
3.
Danielli S, Ma Z, Pantazi E, Kumar A, Demarco B, Fischer F, et al.
EMBO J . 2023 Mar; 42(7):e111450. PMID: 36861806
Membrane ion channels of the calcium homeostasis modulator (CALHM) family promote cell-cell crosstalk at neuronal synapses via ATP release, where ATP acts as a neurotransmitter. CALHM6, the only CALHM highly...
4.
Ogbechi J, Huang Y, Clanchy F, Pantazi E, Topping L, Darlington L, et al.
Front Immunol . 2022 Nov; 13:1001956. PMID: 36389710
Many invasive micro-organisms produce 'quorum sensor' molecules which regulate colony expansion and may modulate host immune responses. We have examined the ability of Quorum Sensor (PQS) to influence cytokine expression...
5.
Pavlidis P, Tsakmaki A, Pantazi E, Li K, Cozzetto D, Digby-Bell J, et al.
Nat Commun . 2022 Oct; 13(1):5820. PMID: 36192482
The function of interleukin-22 (IL-22) in intestinal barrier homeostasis remains controversial. Here, we map the transcriptional landscape regulated by IL-22 in human colonic epithelial organoids and evaluate the biological, functional...
6.
Fischer F, Mies L, Nizami S, Pantazi E, Danielli S, Demarco B, et al.
Proc Natl Acad Sci U S A . 2021 Sep; 118(38). PMID: 34518217
NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome activation is beneficial during infection and vaccination but, when uncontrolled, is detrimental and contributes to inflammation-driven pathologies. Hence, discovering endogenous mechanisms...
7.
Powell N, Pantazi E, Pavlidis P, Tsakmaki A, Li K, Yang F, et al.
Gut . 2019 Dec; 69(3):578-590. PMID: 31792136
Objective: The functional role of interleukin-22 (IL22) in chronic inflammation is controversial, and mechanistic insights into how it regulates target tissue are lacking. In this study, we evaluated the functional...
8.
Pantazi E, Powell N
Front Immunol . 2019 Apr; 10:676. PMID: 31024537
A complex network of interactions exists between the microbiome, the epithelium, and immune cells that reside along the walls of the gastrointestinal tract. The intestinal immune system has been assigned...
9.
Povoleri G, Nova-Lamperti E, Scotta C, Fanelli G, Chen Y, Becker P, et al.
Nat Immunol . 2018 Nov; 19(12):1403-1414. PMID: 30397350
Repair of tissue damaged during inflammatory processes is key to the return of local homeostasis and restoration of epithelial integrity. Here we describe CD161 regulatory T (T) cells as a...
10.
Marks E, Ortiz C, Pantazi E, Bailey C, Lord G, Waldschmidt T, et al.
Front Immunol . 2017 Jan; 7:643. PMID: 28066447
Retinoic acid (RA) plays an important role in the balance of inflammation and tolerance in T cells. Furthermore, it has been demonstrated that RA facilitates IgA isotype switching in B...