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Eirini Bournazou

Explore the profile of Eirini Bournazou including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 528
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Recent Articles
1.
Dickinson M, Briones J, Herrera A, Gonzalez-Barca E, Ghosh N, Cordoba R, et al.
Blood Adv . 2021 Sep; 5(22):4762-4770. PMID: 34581757
Bromodomain and extraterminal (BET) proteins are transcriptional activators for multiple oncogenic processes in diffuse large B-cell lymphoma (DLBCL), including MYC, BCL2, E2F, and toll-like receptor signaling. We report results of...
2.
Bournazou E, Samuels J, Zhou H, Krasnokutsky S, Patel J, Han T, et al.
Int J Mol Sci . 2019 Jun; 20(11). PMID: 31146362
Background: To investigate the expression of vascular adhesion protein-1 (VAP-1) in joint tissues and serum in symptomatic knee osteoarthritis (SKOA) patients and examine whether VAP-1 levels predict increased risk of...
3.
Gao S, Chang Q, Mao N, Daly L, Vogel R, Chan T, et al.
Sci Signal . 2016 Mar; 9(421):ra33. PMID: 27025877
Lung adenocarcinomas with mutant epidermal growth factor receptor (EGFR) respond to EGFR-targeted tyrosine kinase inhibitors (TKIs), but resistance invariably occurs. We found that the Janus kinase (JAK)/signal transduction and activator...
4.
Bournazou E, Bromberg J
JAKSTAT . 2013 Sep; 2(2):e23828. PMID: 24058812
Persistent JAK-STAT3 signaling is implicated in many aspects of tumorigenesis. Apart from its tumor-intrinsic effects, STAT3 also exerts tumor-extrinsic effects, supporting tumor survival and metastasis. These involve the regulation of...
5.
Chang Q, Bournazou E, Sansone P, Berishaj M, Gao S, Daly L, et al.
Neoplasia . 2013 Jul; 15(7):848-62. PMID: 23814496
We have investigated the importance of interleukin-6 (IL-6) in promoting tumor growth and metastasis. In human primary breast cancers, increased levels of IL-6 were found at the tumor leading edge...
6.
Zammarchi F, de Stanchina E, Bournazou E, Supakorndej T, Martires K, Riedel E, et al.
Proc Natl Acad Sci U S A . 2011 Oct; 108(43):17779-84. PMID: 22006329
Signal transducer and activator of transcription 3 (STAT3) plays a central role in the activation of multiple oncogenic pathways. Splicing variant STAT3β uses an alternative acceptor site within exon 23...