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Eileen D Kuempel

Explore the profile of Eileen D Kuempel including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 212
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Recent Articles
1.
Boots T, Kogel A, Drew N, Kuempel E
Nanotoxicology . 2021 Jun; 15(6):740-760. PMID: 34087078
Evaluating the potential occupational health risk of engineered nanomaterials is an ongoing need. The objective of this meta-analysis, which consisted of 36 studies containing 86 materials, was to assess the...
2.
Halappanavar S, Ede J, Mahapatra I, Krug H, Kuempel E, Lynch I, et al.
Nanotoxicology . 2020 Dec; 15(3):289-310. PMID: 33317378
Significant advances have been made in the development of Adverse Outcome Pathways (AOPs) over the last decade, mainly focused on the toxicity mechanisms of chemicals. These AOPs, although relevant to...
3.
Asgharian B, Owen T, Kuempel E, Jarabek A
Toxicol Appl Pharmacol . 2018 May; 361:27-35. PMID: 29738812
Inhalation exposure to some types of fibers (e.g., asbestos) is well known to be associated with respiratory diseases and conditions such as pleural plaques, fibrosis, asbestosis, lung cancer, and mesothelioma....
4.
Dunn K, Eastlake A, Story M, Kuempel E
Ann Work Expo Health . 2018 Mar; PMID: 29529138
Control banding (CB) has been widely recommended for the selection of exposure controls for engineered nanomaterials (ENMs) in the absence of ENM-specific occupational exposure limits (OELs). Several ENM-specific CB strategies...
5.
Drew N, Kuempel E, Pei Y, Yang F
Regul Toxicol Pharmacol . 2017 Aug; 89:253-267. PMID: 28789940
The large and rapidly growing number of engineered nanomaterials (ENMs) presents a challenge to assessing the potential occupational health risks. An initial database of 25 rodent studies including 1929 animals...
6.
Kuempel E, Jaurand M, Moller P, Morimoto Y, Kobayashi N, Pinkerton K, et al.
Crit Rev Toxicol . 2016 Aug; 47(1):1-58. PMID: 27537422
In an evaluation of carbon nanotubes (CNTs) for the IARC Monograph 111, the Mechanisms Subgroup was tasked with assessing the strength of evidence on the potential carcinogenicity of CNTs in...
7.
Kuempel E, Sweeney L, Morris J, Jarabek A
J Occup Environ Hyg . 2015 Nov; 12 Suppl 1:S18-40. PMID: 26551218
The purpose of this article is to provide an overview and practical guide to occupational health professionals concerning the derivation and use of dose estimates in risk assessment for development...
8.
Sweeney L, MacCalman L, Haber L, Kuempel E, Tran C
Regul Toxicol Pharmacol . 2015 Jul; 73(1):151-63. PMID: 26145831
Biomathematical modeling quantitatively describes the disposition of metal nanoparticles in lungs and other organs of rats. In a preliminary model, adjustable parameters were calibrated to each of three data sets...
9.
Dement J, Kuempel E, Zumwalde R, Ristich A, Fernback J, Smith R
Am J Ind Med . 2015 Feb; 58(5):494-508. PMID: 25675894
Background: Airborne fiber size has been shown to be an important factor relative to adverse lung effects of asbestos and suggested in animal studies of carbon nanotubes and nanofibers (CNT/CNF)....
10.