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Eftekhar Eftekharpour

Explore the profile of Eftekhar Eftekharpour including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 2305
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Recent Articles
1.
Islam M, Sultana S, Padmanabhan N, Rashid M, Siddiqui T, Coombs K, et al.
Biochim Biophys Acta Mol Basis Dis . 2024 Oct; 1871(1):167548. PMID: 39454970
Neuronal cell death remains the principal pathophysiologic hallmark of neurodegenerative diseases and the main challenge for treatment strategies. Thioredoxin1 (Trx1) is a major cytoplasmic thiol oxidoreductase protein involved in redox...
2.
Shcholok T, Eftekharpour E
Biology (Basel) . 2024 Mar; 13(3). PMID: 38534450
Redox balance is increasingly identified as a major player in cellular signaling. A fundamentally simple reaction of oxidation and reduction of cysteine residues in cellular proteins is the central concept...
3.
Chen X, Tsvetkov A, Shen H, Isidoro C, Ktistakis N, Linkermann A, et al.
Autophagy . 2024 Mar; 20(6):1213-1246. PMID: 38442890
Macroautophagy/autophagy is a complex degradation process with a dual role in cell death that is influenced by the cell types that are involved and the stressors they are exposed to....
4.
Alejandra Llanes-Cuesta M, Hoi V, Ha R, Tan H, Islam M, Eftekharpour E, et al.
Neuroscience . 2023 Dec; 537:165-173. PMID: 38070592
Thioredoxin system plays an important role in maintaining the cellular redox balance. Recent evidence suggests that thioredoxin (Trx) system may promote cell survival and neuroprotection. In this study, we explored...
5.
Islam M, Eftekharpour E
Neural Regen Res . 2023 Apr; 18(10):2200-2201. PMID: 37056136
No abstract available.
6.
Tabeshmehr P, Eftekharpour E
Biology (Basel) . 2023 Feb; 12(2). PMID: 36829521
Tau, a member of the microtubule-associated proteins, is a known component of the neuronal cytoskeleton; however, in the brain tissue, it is involved in other vital functions beyond maintaining the...
7.
Eftekharpour E
Aging (Albany NY) . 2023 Feb; 15(4):898-904. PMID: 36806186
Aging is an inevitable fact of life which brings along a series of age-associated diseases. Although medical innovations and patient care improvement have increased our life expectancy, the rate of...
8.
Shcholok T, Eftekharpour E
Neural Regen Res . 2022 Jul; 18(2):273-279. PMID: 35900402
Gene deletion has been a valuable tool for unraveling the mysteries of molecular biology. Early approaches included gene trapping and gene targetting to disrupt or delete a gene randomly or...
9.
Islam M, Nagakannan P, Shcholok T, Contu F, Mai S, Albensi B, et al.
Aging Cell . 2021 Dec; 21(1):e13531. PMID: 34905652
Experimental and clinical therapies in the field of Alzheimer's disease (AD) have focused on elimination of extracellular amyloid beta aggregates or prevention of cytoplasmic neuronal fibrillary tangles formation, yet these...
10.
Eftekharpour E, Fernyhough P
Antioxid Redox Signal . 2021 Aug; 37(7-9):578-596. PMID: 34416846
This review highlights the many intracellular processes generating reactive oxygen species (ROS) in the peripheral nervous system in the context of type 1 diabetes. The major sources of superoxide and...