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Edwin Munro

Explore the profile of Edwin Munro including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1584
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Recent Articles
1.
Lang C, Maxian O, Anneken A, Munro E
bioRxiv . 2024 Sep; PMID: 39253498
Studies of PAR polarity have emphasized a paradigm in which mutually antagonistic PAR proteins form complementary polar domains in response to transient cues. A growing body of work suggests that...
2.
Williams A, Donoughe S, Munro E, Horne-Badovinac S
Elife . 2022 Sep; 11. PMID: 36154691
For a group of cells to migrate together, each cell must couple the polarity of its migratory machinery with that of the other cells in the cohort. Although collective cell...
3.
Yao B, Donoughe S, Michaux J, Munro E
Mol Biol Cell . 2022 Feb; 33(6):ar58. PMID: 35138935
Pulsatile RhoA dynamics underlie a wide range of cell and tissue behaviors. The circuits that produce these dynamics in different cells share common architectures based on fast positive and delayed...
4.
Li Y, Munro E
Dev Cell . 2021 Sep; 56(17):2486-2500.e6. PMID: 34480876
During cytokinesis, animal cells rapidly remodel the equatorial cortex to build an aligned array of actin filaments called the contractile ring. Local reorientation of filaments by active equatorial compression is...
5.
Weirich K, Stam S, Munro E, Gardel M
Biophys J . 2021 Apr; 120(10):1957-1970. PMID: 33798565
The actin cytoskeleton is a soft, structural material that underlies biological processes such as cell division, motility, and cargo transport. The cross-linked actin filaments self-organize into a myriad of architectures,...
6.
Lenne P, Munro E, Heemskerk I, Warmflash A, Bocanegra-Moreno L, Kishi K, et al.
Phys Biol . 2020 Dec; 18(4). PMID: 33276350
The way in which interactions between mechanics and biochemistry lead to the emergence of complex cell and tissue organization is an old question that has recently attracted renewed interest from...
7.
Godard B, Dumollard R, Munro E, Chenevert J, Hebras C, McDougall A, et al.
Dev Cell . 2020 Nov; 55(6):695-706.e4. PMID: 33207225
Global tissue tension anisotropy has been shown to trigger stereotypical cell division orientation by elongating mitotic cells along the main tension axis. Yet, how tissue tension elongates mitotic cells despite...
8.
Chen W, Hu Y, Lang C, Brown J, Schwabach S, Song X, et al.
Genetics . 2020 Apr; 215(2):421-434. PMID: 32245789
P granules are phase-separated liquid droplets that play important roles in the maintenance of germ cell fate in Both the localization and formation of P granules are highly dynamic, but...
9.
Cavanaugh K, Staddon M, Munro E, Banerjee S, Gardel M
Dev Cell . 2019 Dec; 52(2):152-166.e5. PMID: 31883774
Epithelial remodeling involves ratcheting behavior whereby periodic contractility produces transient changes in cell-cell contact lengths, which stabilize to produce lasting morphogenetic changes. Pulsatile RhoA activity is thought to underlie morphogenetic...
10.
Hashimoto H, Munro E
Dev Cell . 2019 Oct; 51(2):158-172.e4. PMID: 31639367
Embryos control force generation at tissue boundaries, but how they do so remains poorly understood. Here we show how tissue-specific expression of the type II cadherin, Cadherin2, patterns actomyosin contractility...