Edwin Leeansyah
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Explore the profile of Edwin Leeansyah including associated specialties, affiliations and a list of published articles.
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46
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1447
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Recent Articles
1.
Wu Z, Chen X, Han F, Leeansyah E
Sci Adv
. 2025 Feb;
11(6):eadu4172.
PMID: 39919191
Mucosa-associated invariant T (MAIT) cells are a large population of unconventional T cells widely distributed in the human gastrointestinal tract. Their homing to the gut is central to maintaining mucosal...
2.
Kammann T, Cai C, Sekine T, Mouchtaridi E, Boulouis C, Nilsen V, et al.
Sci Immunol
. 2024 Sep;
9(99):eadn2362.
PMID: 39241054
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 molecules. We explored the human MAIT cell compartment across organ...
3.
Zheng Y, Han F, Wu Z, Wang B, Chen X, Boulouis C, et al.
Sci Adv
. 2024 Jun;
10(24):eadn6331.
PMID: 38865451
Mucosal-associated invariant T (MAIT) cells are antimicrobial T cells abundant in the gut, but mechanisms for their migration into tissues during inflammation are poorly understood. Here, we used acute pediatric...
4.
Sandberg J, Leeansyah E, Eller M, Shacklett B, Paquin-Proulx D
J Immunol
. 2023 Aug;
211(4):511-517.
PMID: 37549397
Mucosal-associated invariant T (MAIT) cells are unconventional T cells with innate-like antimicrobial responsiveness. MAIT cells are known for MR1 (MHC class I-related protein 1)-restricted recognition of microbial riboflavin metabolites giving...
5.
Role of MAIT cells in gastrointestinal tract bacterial infections in humans: More than a gut feeling
Zheng Y, Han F, Ho A, Xue Y, Wu Z, Chen X, et al.
Mucosal Immunol
. 2023 Jun;
16(5):740-752.
PMID: 37353006
Mucosa-associated invariant T (MAIT) cells are the largest population of unconventional T cells in humans. These antimicrobial T cells are poised with rapid effector responses following recognition of the cognate...
6.
Chen Q, Gul I, Liu C, Lei Z, Li X, Raheem M, et al.
J Med Virol
. 2022 Dec;
95(1):e28385.
PMID: 36478250
The global outbreak of the monkeypox virus (MPXV) highlights the need for rapid and cost-effective MPXV detection tools to effectively monitor and control the monkeypox disease. Herein, we demonstrated a...
7.
Gul I, Zhai S, Zhong X, Chen Q, Yuan X, Du Z, et al.
Biosensors (Basel)
. 2022 Nov;
12(11).
PMID: 36354493
Rapid and cost-effective diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are a critical and valuable weapon for the coronavirus disease 2019 (COVID-19) pandemic response. SARS-CoV-2 invasion is...
8.
Han F, Gulam M, Zheng Y, Zulhaimi N, Sia W, He D, et al.
Front Immunol
. 2022 Nov;
13:985385.
PMID: 36341446
MAIT cells are persistently depleted and functionally exhausted in HIV-1-infected patients despite long-term combination antiretroviral therapy (cART). IL-7 treatment supports MAIT cell reconstitution HIV-1-infected individuals and rescues their functionality ....
9.
Han F, Zheng Y, Ho A, Ma S, Sandberg J, Leeansyah E
Crit Rev Immunol
. 2022 Sep;
41(5):69-82.
PMID: 36047323
Mucosa-associated invariant T (MAIT) cells are unconventional innate-like T cells that recognize microbial riboflavin-related metabolites presented by the evolutionarily conserved MHC class I-related (MR1) molecule. MAIT cells are abundant in...
10.
Boulouis C, Leeansyah E, Mairpady Shambat S, Norrby-Teglund A, Sandberg J
J Immunol
. 2022 Feb;
208(5):1170-1179.
PMID: 35140134
Mucosa-associated invariant T (MAIT) cells recognize bacterial riboflavin metabolite Ags presented by MHC class Ib-related protein (MR1) and play important roles in immune control of microbes that synthesize riboflavin. This...