Edwin C Klein
Overview
Explore the profile of Edwin C Klein including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
288
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Recent Articles
1.
Bromley J, Ganchua S, Nyquist S, Maiello P, Chao M, Jacob Borish H, et al.
Immunity
. 2025 Jan;
58(2):513-514.
PMID: 39818207
No abstract available.
2.
Bromley J, Ganchua S, Nyquist S, Maiello P, Chao M, Jacob Borish H, et al.
Immunity
. 2024 Aug;
57(10):2380-2398.e6.
PMID: 39214090
Immunological priming-in the context of either prior infection or vaccination-elicits protective responses against subsequent Mycobacterium tuberculosis (Mtb) infection. However, the changes that occur in the lung cellular milieu post-primary Mtb...
3.
Bromley J, Ganchua S, Nyquist S, Maiello P, Chao M, Jacob Borish H, et al.
bioRxiv
. 2024 Jan;
PMID: 38187598
Immunological priming - either in the context of prior infection or vaccination - elicits protective responses against subsequent () infection. However, the changes that occur in the lung cellular milieu...
4.
Ganchua S, White A, Klein E, Flynn J
PLoS Pathog
. 2020 Aug;
16(8):e1008632.
PMID: 32790739
Lymph nodes, particularly thoracic lymph nodes, are among the most common sites of extrapulmonary tuberculosis (TB). However, Mycobacterium tuberculosis (Mtb) infection in these organs is understudied. Aside from being sites...
5.
Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques
Winchell C, Mishra B, Phuah J, Saqib M, Nelson S, Maiello P, et al.
Front Immunol
. 2020 Jun;
11:891.
PMID: 32477361
In 2017 over 550,000 estimated new cases of multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) occurred, emphasizing a need for new treatment strategies. Linezolid (LZD) is a potent antibiotic for drug-resistant Gram-positive infections...
6.
Armstrong A, Wunschmann A, Rigatti L, Klein E
Vet Pathol
. 2019 Aug;
56(6):959-963.
PMID: 31382854
is a well-documented cause of enterocolitis in several species, including humans, with limited documentation in New World nonhuman primates. We report several cases of -associated pseudomembranous enterocolitis, including a case...
7.
Yamamoto T, Hara H, Foote J, Wang L, Li Q, Klein E, et al.
Transplantation
. 2019 Jul;
103(10):2090-2104.
PMID: 31283686
Background: The aims of this study were to evaluate the efficacy of US Food and Drug Administration-approved drugs in genetically engineered pig-to-baboon kidney xenotransplantation and compare the results with those...
8.
Jagdale A, Iwase H, Klein E, Cooper D
Comp Med
. 2019 Mar;
69(2):86-94.
PMID: 30909988
As clinical pig organ xenotransplantation draws closer, more attention is being paid to diseases that affect pigs and those that provide a potential risk to human recipients of pig organs....
9.
Miller E, Kharlamov E, Hu Z, Klein E, Shiau D, Kelly K
Epilepsy Res
. 2018 Nov;
148:69-77.
PMID: 30391633
The pathophysiological mechanisms of epileptogenesis following ischemic stroke in the aged brain are not well understood, largely due to limited developments in animal modeling of poststroke epilepsy (PSE). A recent...
10.
Ganchua S, Cadena A, Maiello P, Gideon H, Myers A, Junecko B, et al.
PLoS Pathog
. 2018 Nov;
14(11):e1007337.
PMID: 30383808
Tuberculosis is commonly considered a chronic lung disease, however, extrapulmonary infection can occur in any organ. Even though lymph nodes (LN) are among the most common sites of extrapulmonary Mycobacterium...