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Edwige Tellier

Explore the profile of Edwige Tellier including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 455
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Recent Articles
11.
Dekimpe C, Roose E, Kangro K, Bonnez Q, Vandenbulcke A, Tellier E, et al.
J Thromb Haemost . 2021 Mar; 19(9):2248-2255. PMID: 33728786
Background: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is caused by inhibitory and/or clearing anti-ADAMTS-13 (A Disintegrin and Metalloprotease with ThromboSpondin type 1 repeats, member 13) autoantibodies. To determine the presence and...
12.
Velasquez Pereira L, Roose E, Graca N, Sinkovits G, Kangro K, Joly B, et al.
J Thromb Haemost . 2020 Nov; 19(2):478-488. PMID: 33171004
Background: Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is caused by anti-ADAMTS13 autoantibodies inducing a severe deficiency of ADAMTS13. Epitope mapping studies on samples obtained during acute iTTP episodes have shown that...
13.
Horta S, Qu J, Dekimpe C, Bonnez Q, Vandenbulcke A, Tellier E, et al.
Anal Chem . 2020 Sep; 92(20):13880-13887. PMID: 32929962
Autoantibodies are key biomarkers in clinical diagnosis of autoimmune diseases routinely detected by enzyme-linked immunosorbent assays (ELISAs). However, the complexity of these assays is limiting their use in routine diagnostics....
14.
Kangro K, Roose E, Schelpe A, Tellier E, Kaplanski G, Voorberg J, et al.
Res Pract Thromb Haemost . 2020 Jul; 4(5):918-930. PMID: 32685903
Background: In immune-mediated thrombotic thrombocytopenic purpura (iTTP), patients develop an immune response against the multidomain enzyme ADAMTS13. ADAMTS13 consists of a metalloprotease (M) and disintegrin-like (D) domain, 8 thrombospondin type...
15.
Roose E, Schelpe A, Tellier E, Sinkovits G, Joly B, Dekimpe C, et al.
Blood . 2020 May; 136(3):353-361. PMID: 32356859
Recently, we showed that ADAMTS13 circulates in an open conformation during the acute phase of immune-mediated thrombotic thrombocytopenic purpura (iTTP). Although the cause of this conformational change remains elusive, ADAMTS13...
16.
Desbois A, Cacoub P, Leroyer A, Tellier E, Garrido M, Maciejewski-Duval A, et al.
Sci Rep . 2020 Apr; 10(1):6405. PMID: 32286393
The mechanisms regulating inflammation in large vessels vasculitis (LVV) are poorly understood. Interleukin 33 (IL-33) has been shown to license innate and adaptive immunity by enhancing Th2 cytokines production. We...
17.
Dekimpe C, Roose E, Tersteeg C, Joly B, Dewaele A, Horta S, et al.
J Thromb Haemost . 2020 Jan; 18(4):985-990. PMID: 31989742
Background: The biological diagnosis of immune-mediated thrombotic thrombocytopenic purpura (iTTP) is based on determination of ADAMTS13 activity (<10%) and anti-ADAMTS13 autoantibodies. ADAMTS13 antigen levels are not routinely measured in iTTP...
18.
Jarrot P, Tellier E, Plantureux L, Crescence L, Robert S, Chareyre C, et al.
J Autoimmun . 2019 Apr; 100:120-130. PMID: 30930069
Diffuse alveolar hemorrhage (DAH) is a life-threatening complication of systemic lupus erythematosus (SLE) and systemic vasculitis. Although initially described to have antibacterial properties, increasing evidence suggests that neutrophil extracellular traps...
19.
Vassallo P, Simoncini S, Ligi I, Chateau A, Bachelier R, Robert S, et al.
Blood . 2014 Feb; 123(13):2116-26. PMID: 24518759
Epidemiological and experimental studies indicate that early vascular dysfunction occurs in low-birth-weight subjects, especially preterm (PT) infants. We recently reported impaired angiogenic activity of endothelial colony-forming cells (ECFCs) in this...
20.
Ligi I, Simoncini S, Tellier E, Grandvuillemin I, Marcelli M, Bikfalvi A, et al.
J Matern Fetal Neonatal Med . 2013 May; 27(3):233-8. PMID: 23701307
Objective: Low birth weight (LBW) is a risk factor for hypertension at adulthood. Endothelial progenitor cells (EPCs) dysfunction has been characterized in LBW neonates. We hypothesized that changes in soluble,...