Edwige Tellier
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Explore the profile of Edwige Tellier including associated specialties, affiliations and a list of published articles.
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25
Citations
455
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Recent Articles
1.
Cambon A, Guervilly C, Delteil C, Potere N, Bachelier R, Tellier E, et al.
Front Immunol
. 2025 Jan;
15:1493306.
PMID: 39882243
Rationale: COVID-19-associated acute-respiratory distress syndrome (C-ARDS) results from a direct viral injury associated with host excessive innate immune response mainly affecting the lungs. However, cytokine profile in the lung compartment...
2.
Cauchois R, Lagarde M, Muller R, Faccini J, Leroyer A, Arnaud L, et al.
J Thromb Haemost
. 2024 Jul;
22(10):2879-2888.
PMID: 38950779
Background: Immune thrombotic thrombocytopenic purpura (i-TTP) is a life-threatening thrombotic microangiopathy linked to ADAMTS-13 deficiency. It has long been assumed that the activation of endothelial cells is the triggering factor...
3.
Muller R, Cauchois R, Lagarde M, Roffino S, Genovesio C, Fernandez S, et al.
Blood
. 2024 Apr;
143(26):2791-2803.
PMID: 38598839
Thrombotic thrombocytopenic purpura (TTP), a rare but fatal disease if untreated, is due to alteration in von Willebrand factor cleavage resulting in capillary microthrombus formation and ischemic organ damage. Interleukin-1...
4.
Bonnez Q, Dekimpe C, Bekaert T, Tellier E, Kaplanski G, Joly B, et al.
J Thromb Haemost
. 2024 Mar;
22(7):1936-1946.
PMID: 38554935
Background: Laboratory diagnosis of immune-mediated thrombotic thrombocytopenic purpura (iTTP) remains challenging when ADAMTS-13 activity ranges between 10% and 20%. To prevent misdiagnosis, open ADAMTS-13 conformation gained clinical attention as a...
5.
Cambon A, Rebelle C, Bachelier R, Arnaud L, Robert S, Lagarde M, et al.
Front Immunol
. 2023 Dec;
14:1228122.
PMID: 38077384
Objective: IL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic...
6.
Bonnez Q, Dekimpe C, Tellier E, Kaplanski G, Verhamme P, Tersteeg C, et al.
Res Pract Thromb Haemost
. 2023 Sep;
7(6):102171.
PMID: 37711907
Background: Thrombotic thrombocytopenic purpura (TTP) is characterized by severe ADAMTS-13 activity deficiency (<10%). Diagnostic testing is challenging because of unavailability, high cost, and expert technician requirement of ADAMTS-13 enzyme assays....
7.
Cauchois R, Muller R, Lagarde M, Dignat-George F, Tellier E, Kaplanski G
J Clin Med
. 2023 Feb;
12(3).
PMID: 36769407
Thrombotic thrombocytopenic purpura (TTP) is a severe thrombotic microangiopathy. The current pathophysiologic paradigm suggests that the ADAMTS13 deficiency leads to Ultra Large-Von Willebrand Factor multimers accumulation with generation of disseminated...
8.
Tellier E, Widemann A, Cauchois R, Faccini J, Lagarde M, Brun M, et al.
Haematologica
. 2022 Dec;
108(4):1127-1140.
PMID: 36453103
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by a severe ADAMTS13 deficiency due to the presence of anti-ADAMTS13 auto-antibodies, with subsequent accumulation of circulating ultra-large von Willebrand factor (VWF) multimers....
9.
De Waele L, Curie A, Kangro K, Tellier E, Kaplanski G, Mannik A, et al.
Blood Adv
. 2021 Sep;
5(21):4480-4484.
PMID: 34559219
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is caused by an autoantibody-mediated deficiency in ADAMTS13. In healthy individuals, ADAMTS13 has a folded conformation in which the central spacer (S) domain interacts with...
10.
Le Joncour A, Desbois A, Leroyer A, Tellier E, Regnier P, Maciejewski-Duval A, et al.
J Allergy Clin Immunol
. 2021 May;
149(1):292-301.e3.
PMID: 33992671
Background: Takayasu arteritis (TAK) is a large vessel vasculitis resulting in artery wall remodeling with segmental stenosis and/or aneurysm formation. Mast cells (MCs) are instrumental in bridging cell injury and...