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Edward Post

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Articles 19
Citations 821
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Recent Articles
1.
Pearson R, Beevers C, Mignogna J, Benzer J, Pfeiffer P, Post E, et al.
JMIR Res Protoc . 2024 Oct; 13:e59119. PMID: 39446432
Background: Depressive symptoms are common in veterans, and the presence of these symptoms increases disability as well as suicidal thoughts and behaviors. However, there is evidence that these symptoms often...
2.
Arkani M, Kianzad A, Jansen S, Smit J, Post E, Ramaker J, et al.
J Am Heart Assoc . 2023 Jun; 12(13):e028447. PMID: 37345802
Background Appropriate treatment of pulmonary hypertension (PH) is critically dependent on accurate discrimination between pre- and postcapillary PH. However, clinical discrimination is challenging and frequently requires a right heart catheterization....
3.
Antunes-Ferreira M, DAmbrosi S, Arkani M, Post E, In t Veld S, Ramaker J, et al.
Sci Rep . 2023 Jun; 13(1):9359. PMID: 37291189
Liquid biopsy approaches offer a promising technology for early and minimally invasive cancer detection. Tumor-educated platelets (TEPs) have emerged as a promising liquid biopsy biosource for the detection of various...
4.
Muller M, Best M, van der Noort V, Hiltermann T, Niemeijer A, Post E, et al.
Tumour Biol . 2023 Jun; 46(s1):S327-S340. PMID: 37270827
Background: Anti-PD-(L)1 immunotherapy has emerged as a promising treatment approach for non-small cell lung cancer (NSCLC), though the response rates remain low. Pre-treatment response prediction may improve patient allocation for...
5.
Gao Y, Liu C, Li H, Xiong X, Li G, In t Veld S, et al.
Protein Cell . 2023 Mar; 14(6):579-590. PMID: 36905391
Platelets are reprogrammed by cancer via a process called education, which favors cancer development. The transcriptional profile of tumor-educated platelets (TEPs) is skewed and therefore practicable for cancer detection. This...
6.
Mulder F, Kraaijpoel N, Carrier M, Guman N, Jara-Palomares L, Di Nisio M, et al.
J Thromb Haemost . 2023 Feb; 21(4):905-916. PMID: 36841648
Background: Platelet RNA sequencing has been shown to accurately detect cancer in previous studies. Objectives: To compare the diagnostic accuracy of platelet RNA sequencing with standard-of-care limited cancer screening in...
7.
Vermeirssen V, Deleu J, Morlion A, Everaert C, De Wilde J, Anckaert J, et al.
NAR Cancer . 2022 Dec; 4(4):zcac037. PMID: 36451702
While cell-free DNA (cfDNA) is widely being investigated, free circulating RNA (extracellular RNA, exRNA) has the potential to improve cancer therapy response monitoring and detection due to its dynamic nature....
8.
Post E, Sol N, Best M, Wurdinger T
Neurooncol Adv . 2022 Nov; 4(Suppl 2):ii61-ii65. PMID: 36380866
Blood-based liquid biopsies are an upcoming approach for earlier cancer detection, diagnostics, prognostics, therapy-response prediction, and therapy monitoring, including in patients with tumors of the central nervous system. Among these,...
9.
In t Veld S, Arkani M, Post E, Antunes-Ferreira M, DAmbrosi S, Vessies D, et al.
Cancer Cell . 2022 Sep; 40(9):999-1009.e6. PMID: 36055228
Cancer patients benefit from early tumor detection since treatment outcomes are more favorable for less advanced cancers. Platelets are involved in cancer progression and are considered a promising biosource for...
10.
Smits A, Arkani M, In t Veld S, Huis In t Veld A, Sol N, Groeneveldt J, et al.
Ann Am Thorac Soc . 2022 May; 19(10):1650-1660. PMID: 35537078
Pulmonary hypertension encompasses progressive disorders leading to right ventricular dysfunction and early death. Late detection is an important cause of poor clinical outcomes. However, biomarkers that accurately predict the presence...