Edward J Delikatny
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Explore the profile of Edward J Delikatny including associated specialties, affiliations and a list of published articles.
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42
Citations
478
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Recent Articles
1.
Kelly C, Wydrzynska M, Phelan M, Osharovich S, Delikatny E, See V, et al.
Metabolites
. 2025 Feb;
15(2).
PMID: 39997701
Elevated choline kinase alpha (ChoK) levels are observed in most solid tumors, including glioblastomas (GBM), and ChoK inhibitors have demonstrated limited efficacy in GBM models. Given that hypoxia is associated...
2.
Hart M, Isuri R, Ramos D, Osharovich S, Rodriguez A, Harmsen S, et al.
Chem Biomed Imaging
. 2024 Jul;
2(7):490-500.
PMID: 39056064
Lung cancer, the most common cause of cancer-related death in the United States, requires advanced intraoperative detection methods to improve evaluation of surgical margins. In this study we employed DDAO-arachidonate...
3.
Kennedy G, Azari F, Chang A, Bou-Samra P, Desphande C, Predina J, et al.
Mol Imaging Biol
. 2024 Jul;
26(4):585-592.
PMID: 38992245
Purpose: Intraoperative molecular imaging (IMI) uses tumor-targeted optical contrast agents to improve identification and clearance of cancer. Recently, a probe has been developed that only fluoresces when activated in an...
4.
Kelly C, Wydrzynska M, Phelan M, Osharovich S, Delikatny E, See V, et al.
bioRxiv
. 2024 Jan;
PMID: 38293093
Background: Elevated choline kinase alpha (ChoK) is observed in most solid tumours including glioblastomas (GBM), yet until recently, inhibitors of ChoK have demonstrated limited efficacy in GBM models. Given that...
5.
Hsu J, Barragan D, Tward A, Hajfathalian M, Amirshaghaghi A, Mossburg K, et al.
Adv Healthc Mater
. 2023 Dec;
13(8):e2303018.
PMID: 38117252
Silver sulfide nanoparticles (AgS-NP) hold promise for various optical-based biomedical applications, such as near-infrared fluorescence (NIRF) imaging, photoacoustics (PA), and photothermal therapy (PTT). However, their NIR absorbance is relatively low,...
6.
Kennedy G, Azari F, Chang A, Chang A, Bou-Samra P, Desphande C, et al.
Mol Imaging Biol
. 2023 Sep;
25(5):824-832.
PMID: 37697109
Background: Intraoperative molecular imaging (IMI) uses tumor-targeted optical contrast agents to improve identification and clearance of cancer during surgery. Recently, pH-activatable contrast agents have been developed but none has been...
7.
Bou-Samra P, Muhammad N, Chang A, Karsalia R, Azari F, Kennedy G, et al.
J Biomed Opt
. 2023 May;
28(5):050901.
PMID: 37193364
Significance: This third biennial intraoperative molecular imaging (IMI) conference shows how optical contrast agents have been applied to develop clinically significant endpoints that improve precision cancer surgery. Aim: National and...
8.
9.
Bhaduri S, Kelly C, Lesbats C, Sharkey J, Ressel L, Mukherjee S, et al.
NMR Biomed
. 2022 Oct;
36(3):e4855.
PMID: 36269130
Changes in glioblastoma (GBM) metabolism was investigated in response to JAS239, a choline kinase inhibitor, using MRS. In addition to the inhibition of phosphocholine synthesis, we investigated changes in other...
10.
Azari F, Zhang K, Kennedy G, Chang A, Nadeem B, Delikatny E, et al.
J Nucl Med
. 2022 Aug;
63(11):1620-1627.
PMID: 35953303
Intraoperative molecular imaging (IMI) has recently emerged as an important tool in the armamentarium of surgical oncologists. IMI allows real-time assessment of oncologic resection quality, margin assessment, and occult disease...