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Edward Chen

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Articles 44
Citations 350
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Recent Articles
1.
Siegel S, DeWolf S, Schmalz J, Saber W, Dong J, Martens M, et al.
medRxiv . 2025 Mar; PMID: 40061351
Successful hematopoietic cell transplant requires immunosuppression to prevent graft-versus-host disease (GVHD), a lethal, T-cell-mediated post-transplant complication. The phase 3 BMT CTN 1703 trial demonstrated superior GVHD-free/relapse-free survival for post-transplant cyclophosphamide...
2.
Chen E, Pan E, Zhang S
Pharm Res . 2025 Feb; 42(2):291-305. PMID: 39966220
Objective: Human integral membrane enzymes are essential for catalyzing a wide range of biochemical reactions and regulating key cellular processes. However, studying these enzymes remains challenging due to their hydrophobic...
3.
Rajesh K, Chung M, Levine D, Norton E, Patel P, Hohri Y, et al.
JTCVS Open . 2024 Nov; 21:19-34. PMID: 39534352
Background: Valve-sparing root replacement (VSRR) requires a unique skill set. This study aimed to examine the influence of surgeon's procedural volume on outcomes of VSRR. Methods: This retrospective study included...
4.
Mustafa A, Psoter K, Koehler K, Lin N, McCormack M, Chen E, et al.
Chest . 2024 Sep; 167(2):507-517. PMID: 39299388
Background: Sarcoidosis is a granulomatous disease with varying courses of disease progression. Environmental exposures are thought to be contributors to disease onset. Exposure to air pollutants such as fine particulate...
5.
Chen E, Turng L
Polym Eng Sci . 2024 Aug; 64(4):1756-1769. PMID: 39184016
A novel manufacturing technique has been developed to enhance the compliance of expanded polytetrafluoroethylene (ePTFE) for vascular graft applications. This new method involves modifying the existing processing procedures by introducing...
6.
Li Z, Giarto J, Zhang J, Gim J, Chen E, Enriquez E, et al.
Gels . 2024 May; 10(5). PMID: 38786235
Cardiovascular diseases (CVDs) are the number one cause of mortality among non-communicable diseases worldwide. Expanded polytetrafluoroethylene (ePTFE) is a widely used material for making artificial vascular grafts to treat CVDs;...
7.
Epperson J, Athar Z, Arshad M, Chen E
Cureus . 2024 May; 16(4):e57380. PMID: 38694659
Heart failure (HF) poses a significant healthcare burden, with distinct subtypes based on ventricular function. HF with preserved ejection fraction (HFpEF) presents unique epidemiological and mechanistic features compared to HF...
8.
Rajesh K, Chung M, Levine D, Norton E, Patel P, Childress P, et al.
J Thorac Cardiovasc Surg . 2024 May; 169(2):609-616.e4. PMID: 38691070
Objective: Patients with congenital bicuspid aortic valve often require root replacement. This study aims to describe their long-term rates of mortality and reoperation. Methods: This is a multicenter retrospective study...
9.
Lin Q, Gilardi C, Su S, Zhang Z, Chen E, Bandaru P, et al.
ACS Nano . 2023 Nov; 17(21):21083-21092. PMID: 37910857
Carbon nanotube (CNT) transistors demonstrate high mobility but also experience off-state leakage due to the small effective mass and band gap. The lower limit of off-current () was measured in...
10.
Hung A, Chen E, Galeotti J
BME Front . 2023 Oct; 2022:9837076. PMID: 37850165
We propose a weakly- and semisupervised, probabilistic needle-and-reverberation-artifact segmentation algorithm to separate the desired tissue-based pixel values from the superimposed artifacts. Our method models the intensity decay of artifact intensities...