Edward B Stephens
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Explore the profile of Edward B Stephens including associated specialties, affiliations and a list of published articles.
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45
Citations
1616
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Recent Articles
1.
Nothnick W, Arachchige S, Minchella P, Stephens E, Graham A
Front Cell Dev Biol
. 2023 Dec;
11:1225055.
PMID: 38078012
Endometriosis is a benign gynecological disease in which eutopic endometrial tissue composed of glands and stroma grow within the pelvic cavity. The disease affects females of reproductive age and is...
2.
Henke W, Kalamvoki M, Stephens E
bioRxiv
. 2023 Aug;
PMID: 37547007
The open reading frame 3a (ORF3a) is an accessory transmembrane protein that is important to the pathogenicity of SARS-CoV-2. The cytoplasmic domain of ORF3a has three canonical tyrosine-based sorting signals...
3.
Waisner H, Grieshaber B, Saud R, Henke W, Stephens E, Kalamvoki M
Microbiol Spectr
. 2023 Jan;
11(1):e0370722.
PMID: 36622177
The SARS-CoV-2 virion is composed of four structural proteins: spike (S), nucleocapsid (N), membrane (M), and envelope (E). E spans the membrane a single time and is the smallest, yet...
4.
Arachchige S, Henke W, Kalamvoki M, Stephens E
J Virol
. 2021 Feb;
95(8).
PMID: 33536165
Previously, we showed that the presence of the herpes simplex virus type 1 (HSV-1) gD glycoprotein but not gB potently restricted HIV-1 particle infectivity. This restriction was characterized by incorporation...
5.
Arachchige S, Henke W, Kalamvoki M, Stephens E
Retrovirology
. 2019 Apr;
16(1):9.
PMID: 30940160
Background: We previously showed that the gM of HSV-1 could restrict the release of infectious HIV-1 from cells. In this study, we analyzed if the four HSV-1 glycoproteins (gD, gB,...
6.
Nookala A, Schwartz D, Chaudhari N, Glazyrin A, Stephens E, Berman N, et al.
Brain Behav Immun
. 2018 May;
71:37-51.
PMID: 29729322
Methamphetamine (METH) abuse is common among individuals infected with HIV-1 and has been shown to affect HIV replication and pathogenesis. These HIV-1 infected individuals also exhibit greater neuronal injury and...
7.
Arachchige S, Henke W, Pramanik A, Kalamvoki M, Stephens E
J Virol
. 2017 Nov;
92(2).
PMID: 29093081
Virus-encoded proteins that impair or shut down specific host cell functions during replication can be used as probes to identify potential proteins/pathways used in the replication of viruses from other...
8.
Wang Y, Wang Z, Pramanik A, Santiago M, Qiu J, Stephens E
Virology
. 2016 Sep;
498:149-163.
PMID: 27584592
Old World monkey (OWM) and hominid APOBEC3Aproteins exhibit differential restriction activities against lentiviruses and DNA viruses. Human APOBEC3A(hA3A)has weak restriction activity against HIV-1Δvifbut is efficiently restricted by an artificially generated...
9.
Wang Y, Schmitt K, Guo K, Santiago M, Stephens E
J Gen Virol
. 2015 Oct;
97(1):1-17.
PMID: 26489798
The apolipoprotein mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) proteins are a family of seven cytidine deaminases (A3A, A3B, A3C, A3D, A3F, A3G and A3H) that restrict certain viral...
10.
Guo K, Halemano K, Schmitt K, Katuwal M, Wang Y, Harper M, et al.
Immunogenetics
. 2015 May;
67(7):355-70.
PMID: 25994147
B cell functional defects are associated with delayed neutralizing antibody development in pathogenic lentivirus infections. However, the timeframe for alterations in the antibody repertoire and somatic hypermutation (SHM) remains unclear....