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Edouard Couvreu de Deckersberg

Explore the profile of Edouard Couvreu de Deckersberg including associated specialties, affiliations and a list of published articles. Areas
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Citations 24
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Recent Articles
1.
Lei Y, Duong M, Krivec N, Janssens C, Regin M, Huyghebaert A, et al.
Cell Prolif . 2025 Feb; :e13813. PMID: 39908990
Chromosomal abnormalities acquired during cell culture can compromise the differentiation potential of human pluripotent stem cells (hPSCs). In this work, we identified a diminished differentiation capacity to retinal progenitor cells...
2.
Van Der Kelen A, Li Piani L, Mertens J, Regin M, Couvreu de Deckersberg E, Van de Velde H, et al.
Hum Reprod Open . 2025 Jan; 2025(1):hoae074. PMID: 39830711
Study Question: Is there an association between different mitochondrial DNA (mtDNA) genotypes and female infertility or ovarian response, and is the appearance of variants in the oocytes favored by medically...
3.
Regin M, Lei Y, Couvreu de Deckersberg E, Janssens C, Huyghebaert A, Guns Y, et al.
Elife . 2024 Dec; 12. PMID: 39652462
About 70% of human cleavage stage embryos show chromosomal mosaicism, falling to 20% in blastocysts. Chromosomally mosaic human blastocysts can implant and lead to healthy new-borns with normal karyotypes. Studies...
4.
Krivec N, Couvreu de Deckersberg E, Lei Y, Al Delbany D, Regin M, Verhulst S, et al.
Cell Death Dis . 2024 Nov; 15(11):852. PMID: 39572522
Gain of 1q is a highly recurrent chromosomal abnormality in human pluripotent stem cells. In this work, we show that gains of 1q impact the differentiation capacity to derivates of...
5.
Lei Y, Al Delbany D, Krivec N, Regin M, Couvreu de Deckersberg E, Janssens C, et al.
Stem Cell Reports . 2024 Mar; 19(4):562-578. PMID: 38552632
Human pluripotent stem cell (hPSC) cultures are prone to genetic drift, because cells that have acquired specific genetic abnormalities experience a selective advantage in vitro. These abnormalities are highly recurrent...
6.
Mertens J, Belva F, van Montfoort A, Regin M, Zambelli F, Seneca S, et al.
Nat Commun . 2024 Feb; 15(1):1232. PMID: 38336715
Children conceived through assisted reproductive technologies (ART) have an elevated risk of lower birthweight, yet the underlying cause remains unclear. Our study explores mitochondrial DNA (mtDNA) variants as contributors to...
7.
Mertens J, Regin M, De Munck N, Couvreu de Deckersberg E, Belva F, Sermon K, et al.
Hum Mol Genet . 2022 Mar; 31(21):3629-3642. PMID: 35285472
Humans present remarkable diversity in their mitochondrial DNA (mtDNA) in terms of variants across individuals as well as across tissues and even cells within one person. We have investigated the...
8.
Franck S, Couvreu de Deckersberg E, Bubenik J, Markouli C, Barbe L, Allemeersch J, et al.
Biol Open . 2022 Jan; 11(1). PMID: 35019138
Skeletal muscle tissue is severely affected in myotonic dystrophy type 1 (DM1) patients, characterised by muscle weakness, myotonia and muscle immaturity in the most severe congenital form of the disease....
9.
Dziedzicka D, Tewary M, Keller A, Tilleman L, Prochazka L, Ostblom J, et al.
Sci Rep . 2021 Mar; 11(1):6137. PMID: 33731744
Low differentiation propensity towards a targeted lineage can significantly hamper the utility of individual human pluripotent stem cell (hPSC) lines in biomedical applications. Here, we use monolayer and micropatterned cell...