Alpha 2.0
Login Register
» Authors » Edna A Leick

Edna A Leick

Explore the profile of Edna A Leick including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 160
Followers 0
Related Specialties
Pulmonary Medicine
Neurology
Science
Top 10 Co-Authors
Milton A Martins
Iolanda F L C Tiberio
Carla M Prado
Beatriz M Saraiva-Romanholo
Renato F Righetti
Fernanda D T Q S Lopes
Rafael Almeida-Reis
Silvia Fukuzaki
Fabiana G Reis
Adriana F Duran
Published In
Neuroimmunomodulation
Sci Rep
BMC Pulm Med
Respir Physiol Neurobiol
Biomed Res Int
Affiliations
Soon will be listed here.
Recent Articles
1.
Effect of anti-IL17 and/or Rho-kinase inhibitor treatments on vascular remodeling induced by chronic allergic pulmonary inflammation
Dos Santos T, Righetti R, Rezende B, Campos E, Camargo L, Saraiva-Romanholo B, et al.
Ther Adv Respir Dis . 2020 Dec; 14:1753466620962665. PMID: 33357114
Background And Aims: Expansion and morphological dysregulation of the bronchial vascular network occurs in asthmatic airways. Interleukin (IL) -17 and Rho-kinase (ROCK) are known to act in inflammation control and...
2.
Author Correction: Effects of the serine protease inhibitor rBmTI-A in an experimental mouse model of chronic allergic pulmonary inflammation
Florencio A, de Almeida R, Arantes-Costa F, Saraiva-Romanholo B, Duran A, Sasaki S, et al.
Sci Rep . 2019 Nov; 9(1):17011. PMID: 31719669
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
3.
Effects of the serine protease inhibitor rBmTI-A in an experimental mouse model of chronic allergic pulmonary inflammation
Florencio A, de Almeida R, Arantes-Costa F, Saraiva-Romanholo B, Duran A, Sasaki S, et al.
Sci Rep . 2019 Sep; 9(1):12624. PMID: 31477763
To evaluate whether a recombinant serine protease inhibitor (rBmTI-A) modulates inflammation in an experimental model of chronic allergic lung inflammation. Balb/c mice were divided into four groups: SAL (saline), OVA...
4.
Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma
Dos Santos T, Righetti R, Camargo L, Saraiva-Romanholo B, Aristoteles L, de Souza F, et al.
Front Physiol . 2018 Sep; 9:1183. PMID: 30233389
Interleukin-17 (IL-17) and Rho-kinase (ROCK) play an important role in regulating the expression of inflammatory mediators, immune cell recruitment, hyper-responsiveness, tissue remodeling, and oxidative stress. Modulation of IL-17 and ROCK...
5.
Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice
Almeida-Reis R, Theodoro-Junior O, Oliveira B, Oliva L, Toledo-Arruda A, Bonturi C, et al.
Biomed Res Int . 2017 May; 2017:8287125. PMID: 28466019
Proteinases play a key role in emphysema. inhibitor (BbCI) is a serine-cysteine proteinase inhibitor. We evaluated BbCI treatment in elastase-induced pulmonary alterations. / mice received intratracheal elastase (ELA group) or...
6.
Modulation of the oscillatory mechanics of lung tissue and the oxidative stress response induced by arginase inhibition in a chronic allergic inflammation model
Aristoteles L, Righetti R, Pinheiro N, Franco R, Starling C, da Silva J, et al.
BMC Pulm Med . 2013 Aug; 13:52. PMID: 23947680
Background: The importance of the lung parenchyma in the pathophysiology of asthma has previously been demonstrated. Considering that nitric oxide synthases (NOS) and arginases compete for the same substrate, it...
7.
Eosinophilic inflammation in allergic asthma
Possa S, Leick E, Prado C, Martins M, Tiberio I
Front Pharmacol . 2013 Apr; 4:46. PMID: 23616768
Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of processes directed by Th2 cytokine producing T-cells influence the recruitment of eosinophils into the lungs. Furthermore, multiple elements...
8.
Effects of corticosteroid, montelukast and iNOS inhibition on distal lung with chronic inflammation
Souza F, Gobbato N, Maciel R, Prado C, Martins M, Leick E, et al.
Respir Physiol Neurobiol . 2012 Sep; 185(2):435-45. PMID: 23009745
Unlabelled: We evaluated the effects of anti-iNOS (1400W - W) associated with leukotriene antagonist (montelukast - M) or corticosteroid (dexamethasone - D) on distal lung of guinea pigs (GP) with...
9.
Inducible nitric oxide synthase inhibition attenuates physical stress-induced lung hyper-responsiveness and oxidative stress in animals with lung inflammation
Marques R, Reis F, Starling C, Cabido C, de Almeida-Reis R, Dohlnikoff M, et al.
Neuroimmunomodulation . 2012 Jan; 19(3):158-70. PMID: 22262048
Mechanisms involved in stress-induced asthmatic alterations have been poorly characterised. We assessed whether inducible nitric oxide synthase (iNOS) inhibition modulates the stress-amplified lung parenchyma responsiveness, oxidative stress and extracellular matrix...
10.
Effects of repeated stress on distal airway inflammation, remodeling and mechanics in an animal model of chronic airway inflammation
Leick E, Reis F, Honorio-Neves F, Almeida-Reis R, Prado C, Martins M, et al.
Neuroimmunomodulation . 2011 Nov; 19(1):1-9. PMID: 22067616
Background/aims: Epidemiological studies suggest that stress has an impact on asthmatic exacerbations. We evaluated if repeated stress, induced by forced swimming, modulates lung mechanics, distal airway inflammation and extracellular matrix...