Edit Varkondi
Overview
Explore the profile of Edit Varkondi including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
106
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0
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Recent Articles
11.
Breza N, Pato J, Orfi L, Hegymegi-Barakonyi B, Banhegyi P, Varkondi E, et al.
J Recept Signal Transduct Res
. 2008 Aug;
28(4):361-73.
PMID: 18702009
The development of selective protein kinase inhibitors has become an important area of drug discovery for the treatment of different diseases. We report the synthesis and characterization of a series...
12.
Varkondi E, Pinter F, Robert K, Schwab R, Breza N, Orfi L, et al.
J Recept Signal Transduct Res
. 2008 Jun;
28(3):295-306.
PMID: 18569529
Gefitinib and erlotinib are potent EGFR tyrosine kinase inhibitors (potentially) useful for the treatment of non-small-cell lung cancer (NSCLC). Clinical responses, however, in NSCLC patients have been linked to the...
13.
Pinter F, Papay J, Almasi A, Sapi Z, Szabo E, Kanya M, et al.
J Mol Diagn
. 2008 Feb;
10(2):160-8.
PMID: 18258923
The purpose of this study was to investigate whether detectable protein biomarker overexpression is a prerequisite for the presence of increased gene copy number or activating mutations and responsiveness to...
14.
Schwab R, Petak I, Pinter F, Szabo E, Kanya M, Tamasi A, et al.
Orv Hetil
. 2005 Dec;
146(46):2335-42.
PMID: 16370245
Revolution in biotechnology made possible to identify those gene errors, which via their encoded proteins (mostly kinase enzymes) are key players in tumor development, growth and progression, and could be...
15.
Varkondi E, Schafer E, Bokonyi G, Gyokeres T, Orfi L, Petak I, et al.
J Recept Signal Transduct Res
. 2005 Jun;
25(1):45-56.
PMID: 15960394
Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer, and therefore PTK inhibitors are currently under intense investigation as potential drug candidates. PTK...
16.
Sukopp M, Schwab R, Marinelli L, Biron E, Heller M, Varkondi E, et al.
J Med Chem
. 2005 Apr;
48(8):2916-26.
PMID: 15828830
The cyclic somatostatin analogue cyclo[Pro(1)-Phe(2)-D-Trp(3)-Lys(4)-Thr(5)-Phe(6)] (L-363,301) displays high biological activity in inhibiting the release of growth hormone, insulin, and glucagon. According to the sequence of L-363,301, we synthesized a number...
17.
Varkondi E, Gyory F, Nagy A, Kiss I, Ember I, Kozma L
In Vivo
. 2005 Mar;
19(2):465-70.
PMID: 15796211
Background: Several oncogene aberrations have been found in papillary thyroid cancer, the incidence of which has increased after the accident in Chernoby. The occurrence and prognostic significance of these aberrations...