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Eden Flores-Barrera

Explore the profile of Eden Flores-Barrera including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 483
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Recent Articles
1.
Marottoli F, Balu D, Flores-Barrera E, de la Villarmois E, Zhang H, Chaudhary R, et al.
J Am Heart Assoc . 2024 Nov; 13(23):e035080. PMID: 39611383
Background: We recently found that loss of endothelial cell disrupts neurovascular and synaptic function. However, whether endothelial is detrimental or protective for neural function under physiological conditions is unknown. Therefore,...
2.
Koster K, Flores-Barrera E, de la Villarmois E, Caballero A, Tseng K, Yoshii A
J Neurosci . 2023 Oct; 43(49):8317-8335. PMID: 37884348
Protein palmitoylation is the only reversible post-translational lipid modification. Palmitoylation is held in delicate balance by depalmitoylation to precisely regulate protein turnover. While over 20 palmitoylation enzymes are known, depalmitoylation...
3.
Marottoli F, Zhang H, Flores-Barrera E, de la Villarmois E, Damen F, Miguelez Fernandez A, et al.
Arterioscler Thromb Vasc Biol . 2023 Aug; 43(10):1952-1966. PMID: 37650329
Background: Specialized brain endothelial cells and human are independently important for neurovascular function, yet whether expression by endothelial cells contributes to brain function is currently unknown. In the present study,...
4.
Church E, Hamid E, Zurawski Z, Potcoava M, Flores-Barrera E, Caballero A, et al.
J Neurosci . 2021 Dec; 42(6):980-1000. PMID: 34949691
In presynaptic terminals, membrane-delimited G-mediated presynaptic inhibition is ubiquitous and acts via Gβγ to inhibit Ca entry, or directly at SNARE complexes to inhibit Ca-dependent synaptotagmin-SNARE complex interactions. At CA1-subicular...
5.
Flores-Barrera E, Thomases D, Tseng K
J Neurosci . 2020 May; 40(25):4881-4887. PMID: 32430298
Understanding how disruption of prefrontal cortex (PFC) maturation during adolescence is crucial to reveal which neural processes could contribute to the onset of psychiatric disorders that display frontal cortical deficits....
6.
Caballero A, Flores-Barrera E, Thomases D, Tseng K
Neuropsychopharmacology . 2020 May; 45(9):1527-1535. PMID: 32403119
The expression of the calcium binding protein parvalbumin (PV) has been observed in several cortical regions during development in a temporal pattern consistent with increased afferent-dependent activity. In the prefrontal...
7.
Marottoli F, Priego M, Flores-Barrera E, Pisharody R, Zaldua S, Fan K, et al.
Mol Neurobiol . 2019 May; 56(11):7708-7718. PMID: 31104296
Recent evidence indicates that disruption of epidermal growth factor (EGF) signaling by mutant huntingtin (polyQ-htt) may contribute to the onset of behavioral deficits observed in Huntington's disease (HD) through a...
8.
Flores-Barrera E, Thomases D, Cass D, Bhandari A, Schwarcz R, Bruno J, et al.
J Neurosci . 2017 Jul; 37(33):7921-7929. PMID: 28729445
Increased concentrations of kynurenic acid (KYNA) in the prefrontal cortex (PFC) are thought to contribute to the development of cognitive deficits observed in schizophrenia. Although this view is consistent with...
9.
Tubert C, Taravini I, Flores-Barrera E, Sanchez G, Prost M, Avale M, et al.
Cell Rep . 2016 Aug; 16(10):2749-2762. PMID: 27568555
The mechanism underlying a hypercholinergic state in Parkinson's disease (PD) remains uncertain. Here, we show that disruption of the Kv1 channel-mediated function causes hyperexcitability of striatal cholinergic interneurons in a...
10.
Jayasinghe V, Flores-Barrera E, West A, Tseng K
Cereb Cortex . 2015 Oct; 27(1):625-634. PMID: 26508335
The onset of motor deficits in parkinsonism is thought to result from dopamine (DA) loss-induced corticostriatal disruption and the development of excessive cortico-basal ganglia synchronization. To gain insights into the...