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E Stormer

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Articles 10
Citations 131
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Recent Articles
1.
Kappadath S, Clarke M, Stormer E, Steven L, Jaffray B
Eur J Vasc Endovasc Surg . 2009 Nov; 39(2):217-9. PMID: 19939710
Aortoenteric fistulae are infrequent causes of gastrointestinal bleeding and usually occur as a late complication of aortic aneurysm repair. Primary aortoenteric fistulae are very rare and most have an aetiological...
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Bauer S, Stormer E, Graubaum H, Roots I
J Chromatogr B Biomed Sci Appl . 2002 Jan; 765(1):29-35. PMID: 11817306
Hyperforin, hypericin and pseudohypericin are the main ingredients of St. John's wort extract, which is available over the counter for treatment of mild to moderate depression. To facilitate clinical studies...
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Perloff M, von Moltke L, Stormer E, Shader R, Greenblatt D
Br J Pharmacol . 2001 Dec; 134(8):1601-8. PMID: 11739235
1. Chronic use of Saint John's wort (SJW) has been shown to lower the bioavailability for a variety of co-administered drugs including indinavir, cyclosporin, and digoxin. Decreases in intestinal absorption...
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Stormer E, von Moltke L, Perloff M, Greenblatt D
J Clin Pharmacol . 2001 Jul; 41(7):708-14. PMID: 11452702
This study investigated the effects of nefazodone (NFZ) and trazodone (TZD) on P-glycoprotein (P-gp) activity and expression in cell culture. NFZ and TZD showed no differential transport between the basolateral...
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Stormer E, Perloff M, von Moltke L, Greenblatt D
Drug Metab Dispos . 2001 Jun; 29(7):954-6. PMID: 11408360
This study investigated the effects of racemic methadone (MET) on P-glycoprotein (P-gp) activity in cell culture. MET showed no differential rates of passage between the basolateral to apical (B to...
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Stormer E, Roots I, Brockmoller J
Br J Clin Pharmacol . 2001 Jan; 50(6):553-61. PMID: 11136294
Aims: The role of flavin containing monooxygenases (FMO) on the disposition of many drugs has been insufficiently explored. In vitro and in vivo tests are required to study FMO activity...
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Stormer E, von Moltke L, Greenblatt D
J Pharmacol Exp Ther . 2000 Oct; 295(2):793-801. PMID: 11046120
The present study represents a comparison of three approaches to transform recombinant cytochrome P-450 (rCYP) enzyme kinetic data to human liver activity using mirtazapine (MIR) biotransformation as a model. MIR...
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Stormer E, Brockmoller J, Roots I, Schmider J
Psychopharmacology (Berl) . 2000 Oct; 151(4):312-20. PMID: 11026737
Rationale: Perazine (PER) is a phenothiazine antipsychotic drug frequently used in Germany that undergoes extensive metabolism. Objectives And Methods: To anticipate metabolic drug interactions and to explore the relevance of...
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Stormer E, von Moltke L, Shader R, Greenblatt D
Drug Metab Dispos . 2000 Sep; 28(10):1168-75. PMID: 10997935
The metabolism of the antidepressant mirtazapine (MIR) was investigated in vitro using human liver microsomes (HLM) and recombinant enzymes. Mean K(m) values (+/-S.D., n = 4) were 136 (+/-44) microM...