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E Nudler

Explore the profile of E Nudler including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 1027
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Recent Articles
1.
Shamovsky I, Nudler E
Cell Mol Life Sci . 2008 Feb; 65(6):855-61. PMID: 18239856
Heat shock (HS) response is a universal mechanism of protection against adverse environmental conditions. It is manifested mainly by rapid and robust induction of molecular chaperones and other cytoprotective proteins....
2.
Gusarov I, Nudler E
Cell . 2001 Nov; 107(4):437-49. PMID: 11719185
Intrinsic transcription termination plays a crucial role in regulating gene expression in prokaryotes. After a short pause, the termination signal appears in RNA as a hairpin that destabilizes the elongation...
3.
Nudler E
Cell . 2001 Aug; 106(4):443-51. PMID: 11525730
sigma(70) subunit is thought to be released from the core RNA polymerase (RNAP) upon the transition from initiation to elongation or shortly afterward. Here, we identify a population of RNAP...
4.
Nedospasov A, Rafikov R, Beda N, Nudler E
Proc Natl Acad Sci U S A . 2000 Nov; 97(25):13543-8. PMID: 11095728
Nitros(yl)ation is a widespread protein modification that occurs during many physiological and pathological processes. It can alter both the activity and function of a protein. Nitric oxide (( small middle...
5.
Korzheva N, Mustaev A, Nudler E, Nikiforov V, Goldfarb A
Cold Spring Harb Symp Quant Biol . 1999 Jun; 63:337-45. PMID: 10384298
No abstract available.
6.
Nudler E
J Mol Biol . 1999 May; 288(1):1-12. PMID: 10329121
A ternary complex composed of RNA polymerase (RNAP), DNA template, and RNA transcript is the central intermediate in the transcription cycle responsible for the elongation of the RNA chain. Although...
7.
Gusarov I, Nudler E
Mol Cell . 1999 May; 3(4):495-504. PMID: 10230402
In bacteria, an intrinsic transcription termination signal appears in RNA as a hairpin followed by approximately eight uridines (U stretch) at the 3' terminus. This signal leads to rapid dissociation...
8.
Nudler E, Gusarov I, Avetissova E, Kozlov M, Goldfarb A
Science . 1998 Jul; 281(5375):424-8. PMID: 9665887
During RNA synthesis in the ternary elongation complex, RNA polymerase enzyme holds nucleic acids in three contiguous sites: the double-stranded DNA-binding site (DBS) ahead of the transcription bubble, the RNA-DNA...
9.
Nudler E, Mustaev A, Lukhtanov E, Goldfarb A
Cell . 1997 Apr; 89(1):33-41. PMID: 9094712
An 8-9 bp RNA-DNA hybrid in the transcription elongation complex is essential for keeping the RNA 3' terminus engaged with the active site of E. coli RNA polymerase (RNAP). Destabilization...
10.
Nudler E, Avetissova E, Markovtsov V, Goldfarb A
Science . 1996 Jul; 273(5272):211-7. PMID: 8662499
The elongation of RNA chains during transcription occurs in a ternary complex containing RNA polymerase (RNAP), DNA template, and nascent RNA. It is shown here that elongating RNAP from Escherichia...