E N Janoff
Overview
Explore the profile of E N Janoff including associated specialties, affiliations and a list of published articles.
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75
Citations
1665
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Recent Articles
1.
Roche A, Richard A, Rahkola J, Janoff E, Weiser J
Mucosal Immunol
. 2014 Jun;
8(1):176-85.
PMID: 24962092
Invasive infection often begins with asymptomatic colonization of mucosal surfaces. A murine model of bacterial colonization with Streptococcus pneumoniae was used to study the mechanism for mucosal protection by immunoglobulin....
2.
Gustafson C, Higbee D, Yeckes A, Wilson C, de Zoeten E, Jedlicka P, et al.
Mucosal Immunol
. 2013 Sep;
7(3):467-77.
PMID: 24045575
The absence of immunoglobulin A (IgA) in the intestinal tract renders young infants highly susceptible to enteric infections. However, mediators of initial IgA induction in this population are undefined. We...
3.
Janoff E, Rubins J, Fasching C, Charboneau D, Rahkola J, Plaut A, et al.
Mucosal Immunol
. 2013 Jul;
7(2):249-56.
PMID: 23820749
Bacterial immunoglobulin A1 (IgA1) proteases may sabotage the protective effects of IgA. In vitro, both exogenous and endogenously produced IgA1 protease inhibited phagocytic killing of Streptococcus pneumoniae by capsule-specific IgA1...
4.
Rubins J, Janoff E
Drugs Aging
. 2001 Jun;
18(5):305-11.
PMID: 11392439
The effective prevention of Streptococcus pneumoniae infection has a renewed priority in an era in which the emergence of antibacterial-resistant strains has the potential to further compromise efforts to reduce...
5.
6.
Pillay K, Coutsoudis A, Kuhn L, Coovadia H, Janoff E
J Infect Dis
. 2001 Feb;
183(4):653-6.
PMID: 11170993
The presence of both viral particles and antiviral mucosal proteins may represent critical determinants of perinatal human immunodeficiency virus type 1 (HIV-1) transmission. In 60 HIV-1-infected women, concentrations of the...
7.
French N, Mujugira A, Nakiyingi J, Mulder D, Janoff E, Gilks C
J Acquir Immune Defic Syndr
. 2000 Aug;
22(5):509-16.
PMID: 10961614
Clear understanding of the natural history of HIV-1 disease is critical for planning and developing appropriate therapeutic strategies for HIV-1-infected populations in the developing world. Present knowledge about Africa is...
8.
French N, Nakiyingi J, Carpenter L, Lugada E, Watera C, Moi K, et al.
Lancet
. 2000 Jul;
355(9221):2106-11.
PMID: 10902624
Background: Infection with Streptococcus pneumoniae is a frequent and serious problem for HIV-immunosuppressed adults. Vaccination is recommended in the USA and Europe, but there are no prospective data that show...
9.
Carson P, Nichol K, OBrien J, Hilo P, Janoff E
Arch Intern Med
. 2000 Jul;
160(13):2017-24.
PMID: 10888975
Background: Decline in immune function has been reported to predictably accompany advancing age. However, to our knowledge, few studies have specifically characterized the rapidly expanding advanced elderly population or controlled...
10.
Scamurra R, Miller D, Dahl L, Abrahamsen M, Kapur V, Wahl S, et al.
J Immunol
. 2000 May;
164(10):5482-91.
PMID: 10799916
B cells of the largest Ig variable heavy chain gene (VH) family, VH3, are reportedly decreased in patients with late stage HIV-1 disease. This deficit may contribute to their impaired...