E Michelle Southard-Smith
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Explore the profile of E Michelle Southard-Smith including associated specialties, affiliations and a list of published articles.
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43
Citations
1260
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Recent Articles
11.
Perera S, Williams R, Lyne R, Stubbs O, Buehler D, Sauka-Spengler T, et al.
Glia
. 2020 Aug;
68(12):2550-2584.
PMID: 32857879
Olfactory ensheathing cells (OECs) are neural crest-derived glia that ensheath bundles of olfactory axons from their peripheral origins in the olfactory epithelium to their central targets in the olfactory bulb....
12.
Chan W, Komada M, Fukushima T, Southard-Smith E, Anderson C, Wakefield M
Sci Rep
. 2019 Mar;
9(1):3929.
PMID: 30850723
Adrenal chromaffin cells and sympathetic neurons synthesize and release catecholamines, and both cell types are derived from neural crest precursors. However, they have different developmental histories, with sympathetic neurons derived...
13.
Rich C, Perera S, Andratschke J, Stolt C, Buehler D, Southard-Smith E, et al.
Glia
. 2018 Sep;
66(12):2617-2631.
PMID: 30256452
We and others previously showed that in mouse embryos lacking the transcription factor Sox10, olfactory ensheathing cell (OEC) differentiation is disrupted, resulting in defective olfactory axon targeting and fewer gonadotropin-releasing...
14.
May-Zhang A, Deal K, Southard-Smith E
J Vis Exp
. 2018 Jul;
(136).
PMID: 29985370
The purpose of this method is to obtain high-integrity RNA samples from enteric ganglia collected from unfixed, freshly-resected human intestinal tissue using laser capture microdissection (LCM). We have identified five...
15.
Wegner K, Abler L, Oakes S, Mehta G, Ritter K, Hill W, et al.
Am J Physiol Renal Physiol
. 2018 Jul;
315(4):F1067-F1080.
PMID: 29972322
Mouse urinary behavior is quantifiable and is used to pinpoint mechanisms of voiding dysfunction and evaluate potential human therapies. Approaches to evaluate mouse urinary function vary widely among laboratories, however,...
16.
Ritter K, Wang Z, Vezina C, Bjorling D, Southard-Smith E
Front Neurosci
. 2018 Jan;
11:690.
PMID: 29311772
The autonomic and sensory nervous systems are required for proper function of all visceral organs, including the lower urinary tract (LUT). Despite the wide prevalence of bladder dysfunction, effective treatment...
17.
Wiese C, Deal K, Ireland S, Cantrell V, Southard-Smith E
Dev Biol
. 2017 Apr;
429(1):356-369.
PMID: 28449850
The migration and fate of cranial and vagal neural crest-derived progenitor cells (NCPCs) have been extensively studied; however, much less is known about sacral NCPCs particularly in regard to their...
18.
Kulkarni S, Micci M, Leser J, Shin C, Tang S, Fu Y, et al.
Proc Natl Acad Sci U S A
. 2017 Apr;
114(18):E3709-E3718.
PMID: 28420791
According to current dogma, there is little or no ongoing neurogenesis in the fully developed adult enteric nervous system. This lack of neurogenesis leaves unanswered the question of how enteric...
19.
Ritter K, Southard-Smith E
Front Neurosci
. 2017 Jan;
10:592.
PMID: 28111539
Sensory afferent signaling is required for normal function of the lower urinary tract (LUT). Despite the wide prevalence of bladder dysfunction and pelvic pain syndromes, few effective treatment options are...
20.
Bondurand N, Southard-Smith E
Dev Biol
. 2016 Jul;
417(2):139-57.
PMID: 27370713
Hirschsprung disease (HSCR, intestinal aganglionosis) is a multigenic disorder with variable penetrance and severity that has a general population incidence of 1/5000 live births. Studies using animal models have contributed...