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E L Angleton

Explore the profile of E L Angleton including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 194
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Recent Articles
1.
Peng S, Zheng F, Angleton E, Smiley D, Carpenter J, Scott J
Anal Biochem . 2001 May; 293(1):88-95. PMID: 11373083
Signal peptidase (SPase) I is responsible for the cleavage of signal peptides of many secreted proteins in bacteria and serves as a potential target for the development of novel antibacterial...
2.
Wlodawer A, Gustchina A, Reshetnikova L, Lubkowski J, Zdanov A, Hui K, et al.
Nat Struct Biol . 1995 Jun; 2(6):480-8. PMID: 7664111
The crystal structure of a recombinant form of the proteinase encoded by the feline immunodeficiency virus (FIV PR) has been solved at 2 A resolution and refined to an R-factor...
3.
Hui K, Hermann R, Manetta J, Gygi T, Angleton E
FEBS Lett . 1993 Aug; 327(3):355-60. PMID: 8348964
Through a series of synthetic model peptides, we have examined the structural requirements of the P2 and P3 residues in statine-based HIV protease (PR) inhibitors. Results agree with the general...
4.
Hui K, Jakubowski J, Wyss V, Angleton E
Biochem Biophys Res Commun . 1992 Apr; 184(2):790-6. PMID: 1315534
A site-specific proteolytically generated neoamino terminus of the thrombin receptor having a sequence SFLLRNPNDKYEPF- has been reported to be a functional ligand of the receptor. This discovery raises question on...
5.
Angleton E, Nagase H, Birkedal-Hansen H, Van Wart H
Matrix Suppl . 1992 Jan; 1:89-90. PMID: 1480101
No abstract available.
6.
Springman E, Angleton E, Birkedal-Hansen H, Van Wart H
Matrix Suppl . 1992 Jan; 1:76-7. PMID: 1480094
No abstract available.
7.
Springman E, Angleton E, Birkedal-Hansen H, Van Wart H
Proc Natl Acad Sci U S A . 1990 Jan; 87(1):364-8. PMID: 2153297
Latent human fibroblast collagenase (HFC) can be activated by a variety of seemingly disparate means. In addition to the well-characterized activation by trypsin and organomercurial compounds, the enzyme can be...
8.
Angleton E, Van Wart H
Biochemistry . 1988 Sep; 27(19):7413-8. PMID: 2849992
Active site metal substitutions for both gamma- and zeta-collagenases from Clostridium histolyticum have been made by direct metal exchange. The incubation of Co(II), Cu(II), Ni(II), Cd(II), and Hg(II) with these...
9.
Angleton E, Van Wart H
Biochemistry . 1988 Sep; 27(19):7406-12. PMID: 2849991
Both gamma- and zeta-collagenases from Clostridium histolyticum are fully and reversibly inhibited by 1,10-phenanthroline at pH 7.5 in the presence of 10 mM CaCl2 with KI values of 0.11 and...