E K Geissler
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Explore the profile of E K Geissler including associated specialties, affiliations and a list of published articles.
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55
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951
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Recent Articles
1.
Kreiner P, Eggenhofer E, Schneider L, Rejas C, Goetz M, Bogovic N, et al.
Transpl Int
. 2024 Sep;
37:13212.
PMID: 39323909
Biliary complications are still a major cause for morbidity and mortality after liver transplantation (LT). Ischemia/reperfusion injury (IRI) leads to disruption of the biliary epithelium. We introduce a novel model...
2.
Wohl D, James B, Gotz M, Brennfleck F, Holub-Hayles I, Mutzbauer I, et al.
Trials
. 2023 May;
24(1):325.
PMID: 37170284
Background: Graft rejection and chronic CNI toxicity remain obstacles to organ transplant success. Current formulations of tacrolimus, such as Prograf® and Advagraf™, exhibit limitations in terms of pharmacokinetics and tolerability,...
3.
Renner P, Da Silva T, Schnitzbauer A, Verloh N, Schlitt H, Geissler E
BJS Open
. 2021 Apr;
5(2).
PMID: 33839747
Background: Recipient selection for liver transplantation in hepatocellular carcinoma (HCC) is based primarily on criteria affecting the chance of long-term success. Here, the relationship between pretransplant bridging therapy and long-term...
4.
Ahn C, Amer H, Anglicheau D, Ascher N, Baan C, Battsetset G, et al.
Transplantation
. 2020 Apr;
104(10):1974-1983.
PMID: 32243281
No abstract available.
5.
Schiechl G, Hermann F, Rodriguez Gomez M, Kutzi S, Schmidbauer K, Talke Y, et al.
Am J Transplant
. 2016 Mar;
16(9):2574-88.
PMID: 26932231
Fibrosis is a major component of chronic cardiac allograft rejection. Although several cell types are able to produce collagen, resident (donor-derived) fibroblasts are mainly responsible for excessive production of extracellular...
6.
Rovira J, Renner P, Sabet-Baktach M, Eggenhofer E, Koehl G, Lantow M, et al.
Am J Transplant
. 2016 Feb;
16(4):1139-47.
PMID: 26855194
Transplant recipients face an increased risk of cancer compared with the healthy population. Although several studies have examined the direct effects of immunosuppressive drugs on cancer cells, little is known...
7.
Mycielska M, Milenkovic V, Wetzel C, Rummele P, Geissler E
Curr Mol Med
. 2015 Nov;
15(10):884-91.
PMID: 26592250
Citrate is one of the major substrates for intracellular metabolism. The extracellular level of citrate is stable in blood but varies locally, with slightly increased levels in brain and high...
8.
Scheller T, Hellerbrand C, Moser C, Schmidt K, Kroemer A, Brunner S, et al.
Br J Cancer
. 2015 Feb;
112(5):841-50.
PMID: 25688743
Background: Systemic therapy has proven only marginal effects in hepatocellular carcinoma (HCC) so far. The aim of this study was to evaluate the effect of targeting fibroblast growth factor receptor...
9.
Schiechl G, Brunner S, Kesselring R, Martin M, Ruemmele P, Mack M, et al.
Am J Transplant
. 2013 Mar;
13(5):1168-80.
PMID: 23463907
The innate receptor "triggering-receptor-expressed-on-myeloid-cells-1" (TREM-1) enhances downstream signaling of "pattern recognition receptor" (PRR) molecules implicated in inflammatory responses. However the mechanistic role of TREM-1 in chronic heart rejection has yet...
10.
Eggenhofer E, Benseler V, Kroemer A, Popp F, Geissler E, Schlitt H, et al.
Front Immunol
. 2012 Oct;
3:297.
PMID: 23056000
Mesenchymal stem cells (MSC) are under investigation as a therapy for a variety of disorders. Although animal models show long term regenerative and immunomodulatory effects of MSC, the fate of...