E Jane Albert Hubbard
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Explore the profile of E Jane Albert Hubbard including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Kloock A, Hubbard E
bioRxiv
. 2025 Jan;
PMID: 39829881
Populations of proliferating cells such as stem cells and tumors are often nutrient responsive. Highly conserved signaling pathways communicate information about the surrounding environmental, organismal, and cellular nutrient conditions. One...
2.
Tolkin T, Burnett J, Hubbard E
Development
. 2024 Oct;
151(19).
PMID: 39382030
The morphology of cells in vivo can arise from a variety of mechanisms. In the Caenorhabditis elegans hermaphrodite gonad, the distal tip cell (DTC) elaborates into a complex plexus over...
3.
Gupta N, Cammer M, Tolkin T, Hubbard E
MicroPubl Biol
. 2024 Jun;
2024.
PMID: 38841598
Quantification of complex cellular morphology is important for understanding developmental control of cell shape as well as the developmental ramifications of dysregulated cell shape. However, processing and scoring 3D confocal...
4.
Burnett J, Hubbard E
MicroPubl Biol
. 2023 Jul;
2023.
PMID: 37485019
Morphometrics, the quantitative analysis of biological structures, reduces subjectivity and increases reproducibility in characterizing morphological phenotypes. In males, the rounded adult tail tip emerges from a stage-specific retraction of epidermal...
5.
Tolkin T, Mohammad A, Starich T, Nguyen K, Hall D, Schedl T, et al.
Elife
. 2022 Sep;
11.
PMID: 36098634
Gap-junctional signaling mediates myriad cellular interactions in metazoans. Yet, how gap junctions control the positioning of cells in organs is not well understood. Innexins compose gap junctions in invertebrates and...
6.
Amar A, Hubbard E, Kugler H
Biosystems
. 2022 Apr;
217:104672.
PMID: 35469833
Computational methods and tools are a powerful complementary approach to experimental work for studying regulatory interactions in living cells and systems. We demonstrate the use of formal reasoning methods as...
7.
Venzon M, Das R, Luciano D, Burnett J, Park H, Devlin J, et al.
Cell Host Microbe
. 2022 Apr;
30(6):786-797.e8.
PMID: 35413267
Trichuris nematodes reproduce within the microbiota-rich mammalian intestine and lay thousands of eggs daily, facilitating their sustained presence in the environment and hampering eradication efforts. Here, we show that bacterial...
8.
Tolkin T, Hubbard E
Front Cell Dev Biol
. 2021 Jul;
9:699671.
PMID: 34307379
Like many animals and humans, reproduction in the nematode declines with age. This decline is the cumulative result of age-related changes in several steps of germline function, many of which...
9.
Fry A, Webster A, Burnett J, Chitrakar R, Baugh L, Hubbard E
PLoS Genet
. 2021 Jul;
17(7):e1009650.
PMID: 34288923
Quiescence, an actively-maintained reversible state of cell cycle arrest, is not well understood. PTEN is one of the most frequently lost tumor suppressors in human cancers and regulates quiescence of...
10.
Dalfo D, Ding Y, Liang Q, Fong A, Cipriani P, Piano F, et al.
G3 (Bethesda)
. 2020 Oct;
10(12):4323-4334.
PMID: 33077477
Stem cells are tightly controlled Both the balance between self-renewal and differentiation and the rate of proliferation are often regulated by multiple factors. The hermaphrodite germ line provides a simple...