E J Eichwald
Overview
Explore the profile of E J Eichwald including associated specialties, affiliations and a list of published articles.
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Articles
108
Citations
667
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Recent Articles
1.
Csencsits K, Burrell B, Lu G, Eichwald E, Stahl G, Bishop D
Am J Transplant
. 2008 Jun;
8(8):1622-30.
PMID: 18557731
Though complement (C) deposition within the transplant is associated with allograft rejection, the pathways employed have not been established. In addition, evidence suggests that C-mediated cytolysis may be necessary for...
2.
Csencsits K, Wood S, Lu G, Faust S, Brigstock D, Eichwald E, et al.
Am J Transplant
. 2006 Apr;
6(5 Pt 1):959-66.
PMID: 16611331
Late loss of allograft function is primarily attributed to chronic rejection (CR). There are no effective treatments for CR and the underlying cause of the disease is unknown. This study...
3.
Bishop D, Chan Wood S, Eichwald E, Orosz C
J Immunol
. 2001 Feb;
166(5):3248-55.
PMID: 11207279
Both wild-type (WT) and IFN-gamma-deficient (IFN-gamma(-/-)) C57BL/6 mice can rapidly reject BALB/c cardiac allografts. When depleted of CD8(+) cells, both WT and IFN-gamma(-/-) mice rejected their allografts, indicating that these...
4.
Affleck D, Bull D, Albanil A, Shao Y, Brady J, Karwande S, et al.
J Interferon Cytokine Res
. 2001 Feb;
21(1):1-9.
PMID: 11177575
Interleukin-18 (IL-18) and IL-12 have been shown to play an important role in the induction of interferon-gamma (IFN-gamma). IFN-gamma induces the proliferation of T cells and natural killer (NK) cells...
5.
Chan S, Goodman R, Szmuszkovicz J, Roessler B, Eichwald E, Bishop D
Transplantation
. 2000 Nov;
70(9):1292-301.
PMID: 11087143
We have developed a model of transforming growth factor (TGF)beta1 gene transfer into mouse vascularized cardiac allografts to study the use of gene transfer as an immunosuppressive therapy in transplantation....
6.
Roundy K, Kollhoff A, Eichwald E, Weis J, Weis J
J Immunol
. 1999 Dec;
163(12):6671-8.
PMID: 10586063
The microphthalmic mouse (mi) possesses a 3-bp deletion of the Mi gene that alters the DNA binding site of the transcription factor gene product. This animal has diminished numbers of...
7.
Chan S, Li K, Piccotti J, Louie M, Judge T, Turka L, et al.
Nat Med
. 1999 Sep;
5(10):1143-9.
PMID: 10502817
The immune response to adenoviral vectors can induce inflammation and loss of transgene expression in transfected tissues. This would limit the use of adenovirus-mediated gene transfer in disease states in...
8.
Piccotti J, Li K, Chan S, Eichwald E, Bishop D
Transplantation
. 1999 Jul;
67(12):1548-55.
PMID: 10401761
Background: Transient depletion of CD4+ T cells in cardiac allograft recipients prolongs allograft survival; however, grafts exhibit signs of chronic rejection characterized by collagen deposition and neointima development. Although it...
9.
Piccotti J, Li K, Chan S, Eichwald E, Bishop D
Transplantation
. 1999 Jun;
67(11):1453-60.
PMID: 10385085
Background: Interleukin-12 (IL-12) mediates its biologic activities via binding high-affinity receptors on T and natural killer cells. Although emphasis has been placed on the requirement for IL-12Rbeta2 in IL-12 bioactivity,...
10.
Piccotti J, Li K, Chan S, Ferrante J, Magram J, Eichwald E, et al.
J Immunol
. 1998 May;
160(3):1132-8.
PMID: 9570526
IL-12p70, a 70- to 75-kDa heterodimer consisting of disulfide-bonded 35-kDa (p35) and 40-kDa (p40) subunits, enhances Th1 development primarily by its ability to induce IFN-gamma production by NK and Th1...