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E Hatva

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Articles 7
Citations 204
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Recent Articles
1.
Vuorela P, Hatva E, Lymboussaki A, Kaipainen A, Joukov V, Persico M, et al.
Biol Reprod . 1997 Feb; 56(2):489-94. PMID: 9116151
Normal development and function of the placenta requires invasion of the maternal decidua by trophoblasts, followed by abundant and organized vascular growth. Little is known of the significance and function...
2.
Hatva E, Jaaskelainen J, Hirvonen H, Alitalo K, Haltia M
J Neuropathol Exp Neurol . 1996 Nov; 55(11):1124-33. PMID: 8939195
Arteriovenous malformations (AVMs) are congenital lesions composed of abnormal vasculature, with no capillary component, and are clinically significant due to their tendency to spontaneously hemorrhage. The mechanisms regulating the genesis...
3.
Lymboussaki A, Kaipainen A, Hatva E, Vastrik I, Jeskanen L, Jalkanen M, et al.
Br J Cancer . 1996 Jun; 73(11):1347-55. PMID: 8645578
The Myc oncoprotein is associated with cell proliferation and is often down-regulated during cell differentiation. The related Mad transcription factor, which antagonises Myc activity, is highly expressed in epidermal keratinocytes....
4.
Bohling T, Hatva E, Kujala M, Claesson-Welsh L, Alitalo K, Haltia M
J Neuropathol Exp Neurol . 1996 May; 55(5):522-7. PMID: 8627342
To elucidate the mechanisms underlying the regulation of growth and differentiation of capillary hemangioblastoma we studied the expression of selected growth factors and growth factor receptors by immunocytochemistry. As stromal...
5.
Hatva E, Bohling T, Jaaskelainen J, Persico M, Haltia M, Alitalo K
Am J Pathol . 1996 Mar; 148(3):763-75. PMID: 8774132
Capillary hemangioblastomas and hemangiopericytomas are highly vascular central nervous system tumors of controversial origin. Of interest in their pathogenesis are mechanisms regulating endothelial cell growth. The endothelial cell mitogen vascular...
6.
Hatva E, Kaipainen A, Mentula P, Jaaskelainen J, Paetau A, Haltia M, et al.
Am J Pathol . 1995 Feb; 146(2):368-78. PMID: 7856749
Key growth factor-receptor interactions involved in angiogenesis are possible targets for therapy of CNS tumors. Vascular endothelial growth factor (VEGF) is a highly specific endothelial cell mitogen that has been...
7.
Kaipainen A, Vlaykova T, Hatva E, Bohling T, Jekunen A, Pyrhonen S, et al.
Cancer Res . 1994 Dec; 54(24):6571-7. PMID: 7987857
Angiogenesis of human melanomas has been the focus of intense interest since it was shown that the spread and prognosis of primary tumors is correlated with their vascularization (N. Weidner,...