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E C Obermann

Explore the profile of E C Obermann including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 443
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Recent Articles
1.
Rothenbuehler S, Obermann E, Itin P, Goldblum D
Klin Monbl Augenheilkd . 2016 Apr; 233(4):409-10. PMID: 27116495
No abstract available.
2.
Muenst S, Daster S, Obermann E, Droeser R, Weber W, von Holzen U, et al.
Dis Markers . 2013 Nov; 35(5):337-44. PMID: 24191127
Background: Snail is a key regulator of epithelial-mesenchymal transition of tumor cells. Several studies have shown nuclear Snail expression to be a negative prognostic factor in human cancer, where it...
3.
Muenst S, Soysal S, Gao F, Obermann E, Oertli D, Gillanders W
Breast Cancer Res Treat . 2013 Jun; 139(3):667-76. PMID: 23756627
Programmed death 1 (PD-1) is a co-inhibitory receptor in the CD28/CTL-4 family, and functions as a negative regulator of the immune system. Tumor-infiltrating lymphocytes (TIL) in many epithelial cancers express...
4.
Soysal S, Muenst S, Barbie T, Fleming T, Gao F, Spizzo G, et al.
Br J Cancer . 2013 Mar; 108(7):1480-7. PMID: 23519058
Background: Epithelial cell adhesion molecule (EpCAM) is frequently expressed in breast cancer, and its expression has been associated with poor prognosis. Breast cancer can be subdivided into intrinsic subtypes, differing...
5.
Soysal S, Obermann E, Gao F, Oertli D, Gillanders W, Viehl C, et al.
Breast Cancer Res Treat . 2012 Dec; 137(2):637-44. PMID: 23242616
Protein tyrosine phosphatase 1B (PTP1B) is a non-transmembrane protein tyrosine phosphatase that has come into focus as a critical regulator of multiple signaling pathways. The role of PTP1B in breast...
6.
Obermann E, Dirnhofer S, Tzankov A
Histol Histopathol . 2012 Jul; 27(8):1013-20. PMID: 22763873
Lymphomas encompass a broad spectrum of neoplasias. Traditionally it has been assumed that recurrent neoplasia, especially lymphoma, represents a relapse of the original clone. However, this concept has been challenged....
7.
Brault L, Menter T, Obermann E, Knapp S, Thommen S, Schwaller J, et al.
Br J Cancer . 2012 Jun; 107(3):491-500. PMID: 22722314
Background: PIM serine/threonine kinases are often highly expressed in haematological malignancies. We have shown that PIM inhibitors reduced the survival and migration of leukaemic cells. Here, we investigated PIM kinases...
8.
Guth U, Myrick M, Viehl C, Schmid S, Obermann E, Weber W
Eur J Surg Oncol . 2012 May; 38(8):645-50. PMID: 22608851
Background: The ACOSOG Z0011 trial (Z0011) expanded our thinking about breast cancer (BC) and showed that limited metastatic disease left behind in the axilla did not compromise oncological safety in...
9.
Obermann E, Eppenberger-Castori S, Tapia C
Pathologe . 2012 May; 33(3):245-50. PMID: 22576598
Background: The assessment of the proliferation fraction is becoming more and more important; however, there is no consensus concerning optimal validation. Depending on the institute the proliferation fraction is determined...
10.
Rosamilia C, Feichter G, Tzankov A, Obermann E
Pathologe . 2012 Feb; 33(2):118-23. PMID: 22350168
Diagnosing and grading of cervical intraepithelial neoplasias (CIN) are part of the routine practice of pathologists. However, discriminating between reactive changes and CIN1 and determining the different degrees of CIN...