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E C Nelson

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Articles 180
Citations 2353
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Recent Articles
1.
Agrawal A, Chou Y, Carey C, Baranger D, Zhang B, Sherva R, et al.
Mol Psychiatry . 2017 Nov; 23(5):1293-1302. PMID: 29112194
Despite moderate heritability, only one study has identified genome-wide significant loci for cannabis-related phenotypes. We conducted meta-analyses of genome-wide association study data on 2080 cannabis-dependent cases and 6435 cannabis-exposed controls...
2.
Smolkina M, Morley K, Rijsdijk F, Agrawal A, Bergin J, Nelson E, et al.
Behav Genet . 2017 May; 47(4):394-404. PMID: 28466235
Cannabis use disorder (CUD) co-occurs with major depressive disorder (MDD) more frequently than would be expected by chance. However, studies to date have not produced a clear understanding of the...
3.
Crist R, Doyle G, Nelson E, Degenhardt L, Martin N, Montgomery G, et al.
Pharmacogenomics J . 2016 Dec; 18(1):173-179. PMID: 27958381
The μ-opioid receptor (MOR) is the primary target of methadone and buprenorphine. The primary neuronal transcript of the OPRM1 gene, MOR-1, contains a ~13 kb 3' untranslated region with five...
4.
Lindblad S, Ernestam S, Van Citters A, Lind C, Morgan T, Nelson E
QJM . 2016 Nov; 110(3):125-129. PMID: 27803364
No abstract available.
5.
Werner K, McCutcheon V, Agrawal A, Sartor C, Nelson E, Heath A, et al.
Drug Alcohol Depend . 2016 Mar; 162:162-9. PMID: 27012434
Introduction: To examine the contribution of trauma exposure to cannabis initiation and transition to first cannabis use disorder (CUD) symptom in African-American (AA) and European-American (EA) emerging adults. Methods: Data...
6.
Werner K, McCutcheon V, Challa M, Agrawal A, Lynskey M, Conroy E, et al.
Psychol Med . 2015 Dec; 46(3):563-73. PMID: 26688007
Background: Childhood maltreatment (CM) has consistently been linked with adverse outcomes including substance use disorders and adult sexual revictimization. Adult sexual victimization itself has been linked with psychopathology but has...
7.
Grant J, Lynskey M, Madden P, Nelson E, Few L, Bucholz K, et al.
Psychol Med . 2015 Aug; 45(16):3505-15. PMID: 26281760
Background: Genetic influences contribute significantly to co-morbidity between conduct disorder and substance use disorders. Estimating the extent of overlap can assist in the development of phenotypes for genomic analyses. Method:...
8.
Nelson E, Agrawal A, Heath A, Bogdan R, Sherva R, Zhang B, et al.
Mol Psychiatry . 2015 Aug; 21(5):608-14. PMID: 26239289
Opioid dependence, a severe addictive disorder and major societal problem, has been demonstrated to be moderately heritable. We conducted a genome-wide association study in Comorbidity and Trauma Study data comparing...
9.
Nutt J, Siderowf A, Guttman M, Schmidt P, Zamudio J, Wu S, et al.
Parkinsonism Relat Disord . 2013 Nov; 20(3):274-9. PMID: 24182524
Objective: Examine the correlates of Health Related Quality of Life (HRQL) in a large cohort of Parkinson's disease (PD) patients from National Parkinson Foundation (NPF) Centers of Excellence (COEs). Background:...
10.
Agrawal A, Verweij K, Gillespie N, Heath A, Lessov-Schlaggar C, Martin N, et al.
Transl Psychiatry . 2012 Jul; 2:e140. PMID: 22806211
Addictions are serious and common psychiatric disorders, and are among the leading contributors to preventable death. This selective review outlines and highlights the need for a multi-method translational approach to...