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E B de Kier Joffe

Explore the profile of E B de Kier Joffe including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
de Kier Joffe E, Mazzoni E, Aguirre Ghiso J
Medicina (B Aires) . 2001 Feb; 60 Suppl 2:34-40. PMID: 11188928
Deregulation of several signaling pathways have been found to be critical for the development of different types of tumors, both in transgenic and spontaneous models. The role of proteases and...
2.
Aguirre-Ghiso J, Frankel P, Farias E, Lu Z, Jiang H, Olsen A, et al.
Oncogene . 1999 Sep; 18(33):4718-25. PMID: 10467419
Overproduction of urokinase-type plasminogen activator (uPA) and metalloproteases (MMPs) is strongly correlated with tumorigenicity and with invasive and metastatic phenotypes of human and experimental tumors. We demonstrated previously that overproduction...
3.
Aguirre Ghiso J, Alonso D, Farias E, Gomez D, de Kier Joffe E
Eur J Biochem . 1999 Jul; 263(2):295-304. PMID: 10406935
We review the evidence in support of the notion that, upon experimental oncogenic transformation or in spontaneous human cancers, mitogenesis and expression of urokinase (uPA) and its receptor (uPAR) are...